Evidence map›Paper›PMID 40926897›Full record

ReviewFrontiers in cardiovascular medicine2025

Calcification of the elastic component: the impact on the cardiovascular system.

Francesco Demetrio Lofaro, Alessia Mazzilli, Susanna Bonacorsi, Daniela Quaglino, Federica Boraldi

Abstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francesco Demetrio LofaroDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Alessia MazzilliDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Susanna BonacorsiDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Daniela QuaglinoDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Federica BoraldiDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the cardiovascular system, elastic fibres exert a fundamental role providing the long-range elasticity required for physiological functions. Elastic fibres are complex in composition and structure containing, in addition to elastin, a wide range of matrix components, such as microfibrillar proteins, calcium-binding proteins and glycosaminoglycans. Changes in composition and/or structure can affect the biomechanics of the tissue as well as the intrinsic affinity of elastin for Ca

Indexed as

calcification modelscardiovascular systemelastic fibreelastocalcinosisextracellular matrixmineralization

Identifiers

PMID40926897
PMCPMC12414956

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.