ReviewReviews in cardiovascular medicine2025
Research Progress on the Association Between GLP-1 Receptor Agonists and Cardiomyopathy.
Review in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- GLP-1 Receptor Agonists in the Rehabilitation of Patients with Heart Failure: Mechanisms, Clinical Evidence, and Future Perspectives.Nutrients · 2026Review
- Tirzepatide in Obesity-Related Obstructive Sleep Apnea: Beyond Weight Loss Toward Disease Modification?Life (Basel, Switzerland) · 2026Review
- GLP-1 and the brain's powerhouse: a new perspective on the role of mitochondria in neuroprotection.Metabolic brain disease · 2026Review
- Beyond glycemic control: clinical cardiovascular effects of tirzepatide-a narrative review.Therapeutic advances in endocrinology and metabolism · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are a promising new class of drugs, whose clinical potential has recently been explored. Various preclinical studies and clinical trials initially demonstrated the efficacy of GLP-1RAs in treating type 2 diabetes mellitus (T2DM). However, long-term clinical practice has revealed that GLP-1RAs also exhibit significant efficacy and preventive effects in cardiovascular diseases. These effects are mediated through multiple gene pathways; thus, these drugs have shown substantial potential for further development in different clinical contexts. Cardiomyopathy, which constitutes a significant proportion of cardiovascular-related diseases, is increasingly prevalent, with its incidence rising annually. Thus, following the recent surge in research on cardiomyopathy, this review aims to summarize the latest findings regarding the association between GLP-1RAs and cardiomyopathy. This review begins with an introduction to GLP-1RAs, discussing their specific mechanisms of action. This article then addresses the pathogenesis, progression, and mechanisms of cardiomyopathy. Subsequently, a detailed analysis of the relationship between GLP-1RAs and cardiomyopathy is conducted. Finally, this review summarizes and discusses the latest literature on the impact of GLP-1RAs on the risk of various types of cardiomyopathy, as well as the potential underlying biological mechanisms, to provide clinical guidance on the use of GLP-1RAs in the treatment of cardiomyopathy.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.