Evidence map›Paper›PMID 40927270›Full record

ReviewClinical pharmacology : advances and applications2025

Bioactive Compounds From Saudi Arabian Fungi: A Systematic Review of Anticancer Potential.

Sahar S Alghamdi, Jehan H Alamre, Arwa Alsubait, Abdullah R Alanzi, Bandar S Aldawish, Fares Althobiti, Mohammed Ibrahim Al Rudhyyan, Abdulrahman Majid Almadi, Afrah E Mohammed

Abstract readReview
In one paragraph

Review in Clinical pharmacology : advances and applications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sahar S AlghamdiCollege of Pharmacy King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Jehan H AlamreNational Guard Hospital, Riyadh, Saudi Arabia.ORCID 0000-0002-2197-7246
Arwa AlsubaitMedical Research Core Facility and Platforms King Abdullah International Medical Research Center (KAIMRC), Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
Abdullah R AlanziDepartment of Pharmacognosy, College of Pharmacy King Saud University, Riyadh, Saudi Arabia.
Bandar S AldawishCollege of Pharmacy King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.ORCID 0009-0002-2259-6135
Fares AlthobitiCollege of Pharmacy King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Mohammed Ibrahim Al RudhyyanCollege of Pharmacy King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Abdulrahman Majid AlmadiCollege of Pharmacy King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Afrah E MohammedDepartment of Biology, College of Science Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer remains the second leading cause of death worldwide, highlighting the urgent need for novel therapeutic approaches. Fungi are a rich source of bioactive metabolites, some of which exhibit potent anticancer properties. This scoping review evaluates the current research on fungal metabolites with anticancer potential, focusing on species native to Saudi Arabia's unique ecosystem. Following PRISMA 2020 guidelines, a comprehensive literature search was conducted using PubMed, Google Scholar, and Web of Science. Out of approximately 14,000 records, 11 studies met the inclusion criteria (2000-2024). A total of 16 distinct fungal species were identified, with their metabolites tested against various human cancer cell lines. Compounds derived from

Indexed as

anticancer agentscytotoxicityfungal metabolitesmarine fungiSaudi Arabian fungiterrestrial fungi

Identifiers

PMID40927270
PMCPMC12416403

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.