ArticleFrontiers in oncology2025
Application of MRI-guided hysteroscopic one-step resection in preserving the fertility of early endometrial cancer patients.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aims to evaluate the role of MRI-guided hysteroscopic one-step precise resection in diagnosing suspected myometrial invasion (MI) of endometrial cancer (EC) in patients desiring fertility preservation and to analyze the impact of suspected MI on the outcomes of fertility-preserving treatments. Methods: A total of 169 patients with early-stage endometrial cancer who required fertility preservation were enrolled. Among them, 103 cases were ruled out for myometrial invasion by MRI (control group), while 66 cases exhibited suspected myometrial invasion. MRI-guided hysteroscopic one-step resection, which involved the removal of the endometrial lesion, the underlying basal layer, and 3-5 mm of myometrium, was performed for pathological examination. Patients with pathological exclusion of myometrial invasion received fertility-preserving treatment, and their clinical characteristics and treatment outcomes were compared with those of the control group. Results: Based on the precise diagnosis of MRI-guided hysteroscopic one-step resection, 14 of the 66 patients with suspected myometrial invasion were confirmed by pathology and were included in the MI group for surgical treatment. The remaining 52 patients with no evidence of myometrial invasion were included in the non-MI group and received fertility-preserving treatment. The cumulative complete remission rate in the non-MI group was lower than that in the control group at 6 months (24.9% vs. 59.0%, Conclusion: MRI-guided hysteroscopic one-step resection can accurately diagnose the presence of myometrial invasion in early endometrial cancer, which helps about 79% of patients preserve their fertility compared with MRI evaluation alone. Hysteroscopic resection of endometrial lesions, high-dose progesterone treatment, and follow-up are important for the successful fertility-preserving treatment of patients with early endometrial cancer.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.