Evidence map›Paper›PMID 40928192›Full record

SynthesisThe International journal of social psychiatry2026

Mental Health in Sexual and Gender Minority Populations: A Systematic Review of Systematic Reviews With Narrative Synthesis and a Network Meta-Analysis of Suicide Attempts.

Mattia Marchi, Giulia Ferrazzi, Giulia Pollice, Luca Pingani, Silvia Ferrari, Antonio Ventriglio, Gian M Galeazzi

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in The International journal of social psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mattia MarchiDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Italy.ORCID 0000-0003-2970-1276
Giulia FerrazziDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Italy.ORCID 0009-0005-1103-493X
Giulia PolliceDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Italy.ORCID 0009-0005-1625-187X
Luca PinganiDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Italy.ORCID 0000-0003-3428-8308
Silvia FerrariDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Italy.ORCID 0000-0001-7929-4520
Antonio VentriglioDepartment of Clinical and Experimental Medicine, University of Foggia, Italy.ORCID 0000-0002-3934-7007
Gian M GaleazziDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Italy.ORCID 0000-0003-2706-3362

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSexual and gender minorities, collectively known as LGBTQIA+ individuals, experience disproportionate mental health disparities compared to their heterosexual/cisgender peers.

aimsThe aim of this systematic review was to synthesize high-quality evidence from previously published systematic reviews on mental health in the LGBTQIA+ population.

methodPubMed was searched for systematic reviews on LGBTQIA+ mental health, published by September 1st, 2024. For each mental health outcome, a narrative synthesis of the findings was performed. Additionally, when included reviews reported case-control data suitable for pooled analysis, network meta-analyses with random-effects models were conducted to estimate the Odds Ratios (ORs) and 95% confidence intervals (95% CIs) for mental disorders across sexual and gender groups.

resultsTwenty systematic reviews were included, accounting for 5,164,641 LGBTQIA+ individuals. These focused on the following mental health outcomes: major depressive disorder (MDD,

conclusionsLGBTQIA+ individuals experience significant mental health challenges compared to the general population. To reduce these disparities, more inclusive policies, supportive social environments, affirmative mental health care, and ongoing research into minority stressors and protective factors are essential.

Indexed as

Mental DisordersMental HealthSexual and Gender MinoritiesSuicide, AttemptedFemaleHumansMaleNetwork Meta-Analysis as TopicSystematic Reviews as TopicLGBTQIA+mental healthminority stresssexual and gender minoritysuicidality

Identifiers

PMID40928192
PMCPMC12946220

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.