Evidence mapPaperPMID 40928587Full record

ReviewCurrent atherosclerosis reports2025

Novel Strategies to Conquer Residual Adiposity Risk in Cardiovascular Disease.

Jerrin Philip, Aayush Shah, Eleonora Avenatti

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jerrin PhilipDepartment of Cardiology, Houston Methodist DeBakey Heart and Vascular Center, Houston, TX, USA.
Aayush ShahDepartment of Cardiology, Houston Methodist DeBakey Heart and Vascular Center, Houston, TX, USA.
Eleonora AvenattiDepartment of Cardiology, Houston Methodist DeBakey Heart and Vascular Center, Houston, TX, USA. eavenatti@houstonmethodist.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewDespite major advances in the treatment and prevention of atherosclerotic cardiovascular disease (ASCVD), a substantial burden of residual risk remains Obesity has been redefined as a primary and independent drivers of cardiovascular morbidity and mortality warranting focused attention. RECENT

findingsObesity is now recognized as a chronic disease and a central contributor to residual cardiovascular risk through mechanisms including systemic inflammation, insulin resistance, dyslipidemia, and endothelial dysfunction. This review addresses the limitations of conventional obesity management and highlights emerging pharmacological therapies targeting the underlying adiposopathy. Additionally, we examine the impact of stigma and biases as well as social determinants of health on obesity management and explore novel application of imaging, biomarkers and technology to risk stratification tools and innovative care models . Addressing obesity as a modifiable and high-impact disease is essential to advancing ASCVD prevention and treatment.

Indexed as

AdiposityCardiovascular DiseasesObesityHeart Disease Risk FactorsHumansRisk AssessmentRisk FactorsAdiposopathyCardiovascular diseaseGLP1/GIPIncretinsObesityObesity biases

Identifiers

PMID40928587

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.