Evidence map›Paper›PMID 40928675›Full record

ArticleBiotechnology letters2025

Characterization of the pesticidal crystal toxin protein Cry11Aa from Bacillus thuringiensis serovar israelensis VCRC B646 for mosquito larvae control.

Abhisubesh Vijayakumar, Sahadiya Mandodan, Jibi Lukose, Aneha Kunnikuruvan, Kakhuangailiu Gangmei, Bhagyashree Bora, Hemaladkshmi Padmanaban, Mathivanan Ashokkumar, Subbiah Poopathi

Abstract read
PubMed Publisher
In one paragraph

Article in Biotechnology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abhisubesh VijayakumarUnit of Microbiology and Immunology, Vector Control Research Centre, Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, Puducherry, 605006, India.
Sahadiya MandodanUnit of Microbiology and Immunology, Vector Control Research Centre, Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, Puducherry, 605006, India.
Jibi LukoseUnit of Microbiology and Immunology, Vector Control Research Centre, Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, Puducherry, 605006, India.
Aneha KunnikuruvanUnit of Microbiology and Immunology, Vector Control Research Centre, Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, Puducherry, 605006, India.
Kakhuangailiu GangmeiUnit of Microbiology and Immunology, Vector Control Research Centre, Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, Puducherry, 605006, India.
Bhagyashree BoraUnit of Microbiology and Immunology, Vector Control Research Centre, Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, Puducherry, 605006, India.
Hemaladkshmi PadmanabanUnit of Microbiology and Immunology, Vector Control Research Centre, Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, Puducherry, 605006, India.
Mathivanan AshokkumarUnit of Microbiology and Immunology, Vector Control Research Centre, Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, Puducherry, 605006, India.
Subbiah PoopathiUnit of Microbiology and Immunology, Vector Control Research Centre, Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, Puducherry, 605006, India. Subbiahpoopathi@rediffmail.com.ORCID http://orcid.org/0000-0002-2366-3689

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effective mosquito control is essential for reducing the transmission of vector-borne diseases. This study focuses on the comprehensive characterization of mosquitocidal toxins produced by Bacillus thuringiensis serovar israelensis (Bti) VCRC B646 and the associated insecticidal genes. The bacterium was cultured, and the spore-crystal complex was purified to identify the mosquitocidal proteins. The mosquitocidal toxins produced by the isolate were evaluated against Aedes(Ae.) aegypti and Culex(Cx.) quinquefasciatus. SDS-PAGE and LC-MS were conducted to analyse the toxin, and PCR was performed to amplify the toxin gene. Toxicity bioassays indicated lethal concentrations (LC

Indexed as

Bacillus thuringiensisBacterial ProteinsEndotoxinsHemolysin ProteinsInsecticidesMosquito ControlAedesAnimalsBacillus thuringiensis ToxinsCulexLarvaPest Control, BiologicalPhylogenyBacillus thuringiensis ToxinsBacterial ProteinsEndotoxinsHemolysin Proteinsinsecticidal crystal protein, Bacillus ThuringiensisInsecticidesBacillus thuringiensis serovar israelensisCryCytMosquito speciesPhylogenetic analysisToxin protein

Identifiers

PMID40928675

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.