Evidence map›Paper›PMID 40928718›Full record

ReviewVeterinary research communications2025

The role of Moringa oleifera in enhancing fish performance and health: a comprehensive review of sustainable aquaculture applications.

Sohair Y Saleh, Nehal A Younis, Ahmed H Sherif, Howyda G Gaber

Abstract readReview
In one paragraph

Review in Veterinary research communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sohair Y SalehDepartment of Physiology, Faculty of Veterinary Medicine, Cairo University, PO 11221, Giza, Egypt. sohair_saleh@cu.edu.eg.
Nehal A YounisDepartment of Aquatic Animal Medicine and Management, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt, PO 11221.
Ahmed H SherifFish Disease Department, Animal Health Research Institute AHRI, Agriculture Research Center ARC, PO 12619, Kafrelsheikh, Egypt. ahsherif77@yahoo.com.
Howyda G GaberDepartment of Physiology, Faculty of Veterinary Medicine, Cairo University, PO 11221, Giza, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This comprehensive review examines the versatile applications and effects of Moringa oleifera across multiple fish species in aquaculture systems amid growing challenges of rising feed costs and antimicrobial resistance. M. oleifera, commonly called the Miracle tree, contains an exceptional nutritional profile with high protein content (22.99-29.36% dry weight), complete profiles of essential amino acids, and remarkably elevated levels of vitamins and minerals. Its bioactive profile includes substantial quantities of polyphenols, flavonoids, alkaloids (niazimicin, niaziminin, β-sitosterol), and glucosinolates that collectively enhance fish health and performance. Recent studies across multiple fish species demonstrate variable optimal inclusion rates (5-30%) with specific growth rates increasing 15-35% and feed conversion ratios improving 10-25% compared to controls. Physiological benefits include enhanced digestive enzyme activity, improved liver and kidney functions, and reduced cortisol levels during environmental stress. Immunologically, M. oleifera supplementation significantly increases lysozyme activity, complement C3, total IgM levels, and pro-inflammatory cytokine expression (TNFα, IL1-β, IL-6), strengthening resistance against major aquaculture pathogens including Aeromonas hydrophila, Pseudomonas aeruginosa, and Vibrio species. Challenge studies demonstrate relative percent survival improvements ranging from 48 to 73% against virulent pathogens. Haematological improvements include increased erythrocyte counts, higher haemoglobin levels at moderate inclusion rates, and beneficial effects on glucose metabolism and lipid profiles. Moringa seeds are highly effective natural water clarifiers, removing 95-99% of turbidity through cationic proteins that act as coagulants. However, their antinutritional compounds (tannins, phytates, saponins, oxalates) can harm fish at elevated levels, requiring careful dosage monitoring in aquaculture applications. This review synthesizes current evidence, identifies optimal application strategies, and provides direction for future research to maximize Moringa's potential as a sustainable, cost-effective resource for enhancing productivity, fish health, and environmental sustainability in modern aquaculture systems.

Indexed as

Animal FeedAquacultureFishesMoringa oleiferaAnimalsDietDietary SupplementsAquacultureDisease resistanceEconomic analysisFeed additiveGrowth performanceImmunostimulantMoringa OleiferaSustainable aquacultureWater clarification

Identifiers

PMID40928718
PMCPMC12423190

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.