ArticleThe Gerontologist2025
The relationship between blood pressure and cognitive decline differs by race.
Article in The Gerontologist, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Artificial Intelligence driven prediction of multiple outcomes in older adults with coronary heart disease.The Gerontologist · 2026Article
- Place Matters: Investigating the Social and Environmental Drivers of Hypertension in Nashville.Family & community healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
BACKGROUND AND
objectivesCognition may be influenced by health-related factors such as blood pressure (BP). However, variations in BP may differentially affect cognition across race. This study investigates BP and cognitive decline in older Black and White adults. RESEARCH DESIGN AND
methodsA total of 2,284 participants (1,139 Blacks, 1,145 Whites, MAge = 73.4) from three harmonized cohorts of older adults from the Rush Alzheimer's Disease Center, were divided into three groups (normal, high, variable) based on systolic BP mean and standard deviation. Cognitive scores were computed from 18 neuropsychological tests and averaged to summarize five domains (episodic memory, semantic memory, working memory, processing speed, visuospatial ability) and a measure of global cognition. Linear mixed-effects models examined racial differences between BP and cognition over an average of 6.7 years.
resultsWhite adults with high BP declined faster in global cognition, perceptual speed, semantic memory, and working memory compared to Black adults with high BP, whereas White adults with variable BP had faster rates of decline in global cognition, all cognitive domains, compared to Black adults with variable BP. No differences in rate of cognitive decline were observed between Black and White older adults with normal BP. DISCUSSION AND IMPLICATIONS: Variations in BP differentially relate to cognitive decline in Black and White older adults, highlighting the interplay between BP and cognitive health, and the importance of race in understanding this relationship.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.