ArticleCell reports methods2025
Toward owner governance in genomic data privacy with Governome.
Article in Cell reports methods, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Multi-omics-driven precision medicine.iMeta · 2026Review
- Beyond the 'Pregnancy Black Box': a global roadmap for artificial intelligence-driven pharmacogenomics in maternal-neonatal health.The pharmacogenomics journal · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advancements in sequencing technologies grant individuals unprecedented access to their genomic data. However, existing data management systems or protocols are inadequate in privacy protection, limiting individuals' control over their genomic information, hindering data sharing, and posing challenges for biomedical research. Therefore, demand exists for an owner-governed system fulfilling owner authority, life cycle data encryption, and verifiability simultaneously. Here, we realized Governome, an owner-governed data management system empowering individuals with real-time control over their genomic data. Governome leverages a blockchain to manage transactions and permissions, granting data owners dynamic permission management with full transparency on data usage. It uses homomorphic encryption and zero-knowledge proofs to enable genomic data storage and computation in an encrypted and verifiable form throughout its life cycle. Governome can support versatile genomic applications. We implemented and tested individual variant query, cohort study, genome-wide association study (GWAS) analysis, and forensics on 2,504 1000 Genomes Project (1kGP) genomes, demonstrating its robustness and scalability. Governome is open-source at https://github.com/HKU-BAL/Governome.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.