Evidence map›Paper›PMID 40930556›Full record

ArticleBMJ open2025

Dosage and safety of transcranial magnetic stimulation and transcranial direct current stimulation for managing patients with chronic musculoskeletal pain: a scoping review protocol.

Liming Jiang, Yifan Wang, Yuwu Ding, Kun Yang, Zengqiao Zhang, Ramakrishnan Mani, Jiayi Xia, Bitao Ma, Sizhong Wang

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Liming Jiang *Department of Rehabilitation, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.ORCID http://orcid.org/0000-0001-7773-0149
Yifan Wang *School of Rehabilitation Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yuwu DingDepartment of Rehabilitation, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Kun YangDepartment of Rehabilitation, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zengqiao ZhangDepartment of Rehabilitation, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.ORCID http://orcid.org/0000-0002-8119-2838
Ramakrishnan ManiSchool of Physiotherapy, University of Otago, Dunedin, New Zealand.
Jiayi XiaClinical Research Center, The Second Rehabilitation Hospital of Shanghai, Shanghai, China sizhong.wang@hotmail.com 532821681@qq.com mbttm@126.com.
Bitao MaDepartment of Traditional Chinese Medicine, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China sizhong.wang@hotmail.com 532821681@qq.com mbttm@126.com.
Sizhong WangSchool of Exercise and Health, Shanghai University of Sport, Shanghai, China sizhong.wang@hotmail.com 532821681@qq.com mbttm@126.com.ORCID http://orcid.org/0000-0002-9274-3447

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough emerging evidence supports the short-term efficacy of transcranial magnetic stimulation (TMS), including repetitive TMS (rTMS) and theta-burst transcranial magnetic stimulation (TBS-TMS), and transcranial direct current stimulation (tDCS) for managing patients with chronic musculoskeletal pain (CMP), their clinical utility in managing CMP remains inconclusive. This uncertainty may arise from methodological limitations, including heterogeneity in treatment parameters such as stimulation targets and dosages. Additionally, safety profiles for these non-invasive brain stimulation interventions in patients with CMP remain insufficiently reported, with limited data on adverse events, cumulative risks and long-term safety outcomes. Hence, in this scoping review protocol, we aim to systematically (1) identify and map the stimulation targets and dosages of TMS and tDCS used in previous studies to treat patients with CMP; (2) summarise the rationale for using the stimulation targets and dosages of TMS and tDCS; and (3) summarise the reports on the safety of TMS and tDCS in managing patients with CMP, including whether safety was reported and how it was described. METHODS AND ANALYSIS: We will adopt Arksey and O'Malley's methodological framework and report findings according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. Two authors will independently screen articles and extract data from PubMed, Scopus, Web of Science and Embase, including publications from inception to 1 August 2025. Discrepancies regarding study inclusion will be resolved through consultation with a third author. We will synthesise results using descriptive statistical methods. ETHICS AND DISSEMINATION: This scoping review does not require ethical approval. The findings will be disseminated through presentation at national or international conferences and peer-reviewed publication. TRIAL REGISTRATION DETAILS: Open Science Framework (Registration DOI: https://doi.org/10.17605/OSF.IO/8HFBZ).

Indexed as

Chronic PainMusculoskeletal PainTranscranial Direct Current StimulationTranscranial Magnetic StimulationHumansResearch DesignScoping Reviews as TopicChronic PainMusculoskeletal disordersTranscranial Magnetic Stimulation

Identifiers

PMID40930556
PMCPMC12421619

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.