Evidence map›Paper›PMID 40930837›Full record

ArticlePhysiological reports2025

Systemic cardiovascular and carotid baroreflex support of arterial pressure during recovery from passive heat stress in young and older adults.

Emily A Larson, Brendan W Kaiser, Emma L Reed, Brandon M Gibson, Kieran S S Abbotts, W Larry Kenney, Christopher T Minson, John R Halliwill

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emily A LarsonDepartment of Human Physiology, University of Oregon, Eugene, Oregon, USA.
Brendan W KaiserDepartment of Human Physiology, University of Oregon, Eugene, Oregon, USA.
Emma L ReedDepartment of Human Physiology, University of Oregon, Eugene, Oregon, USA.
Brandon M GibsonDepartment of Human Physiology, University of Oregon, Eugene, Oregon, USA.
Kieran S S AbbottsDepartment of Human Physiology, University of Oregon, Eugene, Oregon, USA.
W Larry KenneyDepartment of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, USA.
Christopher T MinsonDepartment of Human Physiology, University of Oregon, Eugene, Oregon, USA.
John R HalliwillDepartment of Human Physiology, University of Oregon, Eugene, Oregon, USA.ORCID https://orcid.org/0000-0003-3001-1715

Funding

Heat Therapy versus Exercise Training in HypertensionR01HL144128 · NHLBI · UNIVERSITY OF OREGON · PI HALLIWILL, JOHN R., MINSON, CHRISTOPHER TODD · 2018 to 2021
$2.6M
Sympathetic Vascular Regulation following Heat Stress in Young and Aged HumansF31HL158087 · NHLBI · UNIVERSITY OF OREGON · PI LARSON, EMILY A · 2021 to 2023
$86k
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL144128HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL158087NHLBI NIH HHS F31 HL158087NHLBI NIH HHS R01 HL144128
6 · The paper itself

Abstract

We evaluated the systemic cardiovascular and carotid baroreflex support of arterial pressure during recovery from whole-body, passive heating in young and older adults. Supine mean arterial pressure (MAP), cardiac output (Q; acetylene washin), systemic vascular conductance (SVC), heart rate (HR), and stroke volume (SV) were evaluated in 16 young (8F, 18-29 years) and nine older (6F, 61-73 years) adults at normothermic baseline and for 60-min passive heating and 120-min normothermic recovery. Externally applied neck pressure was used to evaluate HR, brachial vascular conductance, and MAP responses to carotid baroreceptor unloading. MAP was reduced with heating in young adults (p < 0.001) and similar to baseline within 30 min recovery in both age groups. Heating-induced Q, SVC, HR, and SV responses returned to baseline within 60 min recovery in both age groups. Heating attenuated HR and brachial vascular responses to neck pressure in young adults (both p < 0.01), but these responses did not differ from baseline throughout recovery in either age cohort. MAP responses to neck pressure were not impacted by heating in either age group but increased after 90 min recovery in young adults (p < 0.05). The systemic cardiovascular and carotid baroreflex responses accompanying passive heating do not persist beyond 30 min of post-heating recovery in young or older adults.

Indexed as

AgingArterial PressureBaroreflexHeat-Shock ResponseAdolescentAdultAgedBlood PressureCardiac OutputCarotid ArteriesFemaleHeart RateHumansMaleMiddle AgedYoung Adultblood pressurebody temperature regulationhemodynamicshyperthermiathermoregulation

Identifiers

PMID40930837
PMCPMC12422808

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.