ArticleAnnals of laboratory medicine2026
Effect of Exposure to Room Temperature During Storage on Cryopreserved Umbilical Cord Blood Quality.
Article in Annals of laboratory medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
Cryopreserved umbilical cord blood (CB) for transplantation is occasionally exposed to room temperature during storage in cord blood banks. We evaluated the effect of room temperature exposure on the quality of cryopreserved CB. Forty frozen CB units stored in liquid nitrogen tanks were exposed to room temperature until they reached a target temperature of -130°C (group I), -60°C (group II), -40°C (group III), or -25°C (group IV) (N=10 in each group) and then re-stored. After re-thawing, the quality of the frozen CB was assessed based on the recovery rates of cell count, cell viability, and colony-forming unit granulocyte/macrophage (CFU-GM) content. The mean exposure times required to reach the target temperature were 0.83±0.14, 5.92±0.88, 10.28±1.0, and 16.0±1.62 mins for groups I-IV, respectively. CD34
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