Evidence map›Paper›PMID 40930983›Full record

ArticleGenome research2025

Mapping multitissue regulatory variants reveals a liver-centric coexpression network associated with duck egg-laying performance.

Yang Xi, Jingjing Qi, Zhao Yang, Yutian Zeng, Huicong Zhang, Qiuyu Tao, Mengru Xu, Anqi Huang, Shenqiang Hu, Chunchun Han and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genome research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Research Progress on Genetic Factors of Poultry Egg Quality: A Review.Animals : an open access journal from MDPI · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yang XiCollege of Life Science, Sichuan Agricultural University, Ya'an, 625014, People's Republic of China.
Jingjing QiState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, People's Republic of China.
Zhao YangState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, People's Republic of China.
Yutian ZengState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, People's Republic of China.
Huicong ZhangCenter for Quantitative Genetics and Genomics, Aarhus University, Aarhus, 8000, Denmark.
Qiuyu TaoState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, People's Republic of China.
Mengru XuState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, People's Republic of China.
Anqi HuangCollege of Life Science, Sichuan Agricultural University, Ya'an, 625014, People's Republic of China.
Shenqiang HuState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, People's Republic of China.
Chunchun HanState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, People's Republic of China.
Lili BaiState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, People's Republic of China.
Jiwei HuState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, People's Republic of China.
Jiwen WangState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, People's Republic of China.
Liang LiState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, People's Republic of China liuee1985@sicau.edu.cn lingzhao.fang@qgg.au.dk liliang@sicau.edu.cn.
Lingzhao FangCenter for Quantitative Genetics and Genomics, Aarhus University, Aarhus, 8000, Denmark.
Hehe LiuCollege of Life Science, Sichuan Agricultural University, Ya'an, 625014, People's Republic of China; liuee1985@sicau.edu.cn lingzhao.fang@qgg.au.dk liliang@sicau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poultry egg production is shaped by the intertwined action of multiple physiological systems, greatly magnifying the complexity of its underlying genetic regulation. Although multitissue mapping of regulatory variants offers a powerful route to untangle this complexity, comprehensive data sets in ducks remain scarce. Meanwhile, the contributions of peripheral systems beyond neuroendocrine regulation on poultry egg production are still largely unexplored. Here, we generate 979 RNA-seq samples from the liver, ovary, oviduct shell gland, and spleen, along with matched whole-genome sequencing data from 307 egg-laying ducks. We map

Indexed as

DucksGene Regulatory NetworksLiverOvipositionAlternative SplicingAnimalsFemaleGene Expression RegulationGenome-Wide Association StudyOvaryQuantitative Trait Loci

Identifiers

PMID40930983
PMCPMC12487825

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.