ArticleEuropean journal of nutrition2025
Changes in food choices and dietary patterns during the lifestyle intervention and their association with type 2 diabetes risk in participants with high or low genetic risk for type 2 diabetes.
Article in European journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate how a group-based lifestyle intervention affects food choices and if the dietary patterns at the end of the intervention are associated with incidence type 2 diabetes (T2D). We also investigated if the possible associations between diet and T2D risk were modified by the genetic risk for T2D.
methodsParticipants in the T2D-GENE study were men with prediabetes aged 50-75 years, body mass index ≥ 25 kg/m
resultsThere were statistically significant changes towards more recommended food consumption (higher frequency of whole-grain products, vegetables, and non-tropical vegetable oils) in the participants receiving lifestyle counselling as compared to their baseline and to the population controls. The intervention group reported increased consumption of healthy dietary pattern (high in e.g. vegetables, whole-grain products, and fish) and decreased consumption of unhealthy (high in e.g. meat, sausages and low-fibre products) at year three as compared to baseline. End-of-intervention healthy dietary pattern was associated with a decrease in the risk of T2D (OR 0.67, 95% CI 0.46; 0.97 in multivariable model) and end-of-intervention unhealthy pattern with increased risk (OR 1.82, 95% CI 1.26; 2.62 in multivariable model). When stratified by the GRS, the associations remained significant for the high genetic risk group.
conclusionA group-based lifestyle intervention improved diet quality. Healthy dietary pattern associated with lower risk for T2D whereas unhealthy pattern associated with higher risk. After stratification by the GRS, associations were evident in participants with a high genetic risk for T2D.
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