Evidence map›Paper›PMID 40931613›Full record

ArticleACS biomaterials science & engineering2025

Violacein-Loaded Outer Membrane Vesicles from

Genesy Pérez Jorge, Marco Gontijo, Marina Flóro E Silva, Raquel Bester Liszbinski, Renata Spagolla Napoleão Tavares, Cyro von Zuben de Valega Negrão, Carlismari Oliveira Grundmann, Isabella Carolina Rodrigues Dos Santos Goes, Lilian de Oliveira Coser, Elizabeth Bilsland and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS biomaterials science & engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Genesy Pérez JorgeDepartamento de Genética, Evolução, Microbiologia e Immunologia, Instituto de Biologia, Universidade Estadual de Campinas - UNICAMP, Campinas, São Paulo 13083-862, Brazil.ORCID 0000-0002-2138-7393
Marco GontijoDepartamento de Genética, Evolução, Microbiologia e Immunologia, Instituto de Biologia, Universidade Estadual de Campinas - UNICAMP, Campinas, São Paulo 13083-862, Brazil.ORCID 0000-0001-6605-3402
Marina Flóro E SilvaDepartamento de Genética, Evolução, Microbiologia e Immunologia, Instituto de Biologia, Universidade Estadual de Campinas - UNICAMP, Campinas, São Paulo 13083-862, Brazil.
Raquel Bester LiszbinskiBrazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, São Paulo 13083-970, Brazil.
Renata Spagolla Napoleão TavaresBrazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, São Paulo 13083-970, Brazil.
Cyro von Zuben de Valega NegrãoBrazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, São Paulo 13083-970, Brazil.
Carlismari Oliveira GrundmannSchool of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo 14040-903, Brazil.ORCID 0000-0003-2799-3527
Isabella Carolina Rodrigues Dos Santos GoesDepartamento de Genética, Evolução, Microbiologia e Immunologia, Instituto de Biologia, Universidade Estadual de Campinas - UNICAMP, Campinas, São Paulo 13083-862, Brazil.ORCID 0000-0001-9591-7046
Lilian de Oliveira CoserDepartamento de Patologia Clínica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas -UNICAMP, Campinas, São Paulo 13083-887, Brazil.
Elizabeth BilslandSynthetic Biology Laboratory, Department of Structural and Functional Biology, Institute of Biology, Universidade Estadual de Campinas -UNICAMP, Campinas, São Paulo 13083-862, Brazil.ORCID 0000-0002-8697-3553
Francisca Janaína Soares RochaTropical Medicine Department, Medical Science Center, Federal University of Pernambuco, Recife, Pernambuco 50670-901, Brazil.
Monica Tallarico PupoSchool of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo 14040-903, Brazil.ORCID 0000-0003-2705-0123
Selma GiorgioDepartamento de Biologia Animal, Instituto de Biologia, Universidade Estadual de Campinas - UNICAMP, Campinas, São Paulo 13083-862, Brazil.
Sandra Martha Gomes DiasBrazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, São Paulo 13083-970, Brazil.ORCID 0000-0002-1589-7856
Fausto AlmeidaDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, São Paulo 14049-900, Brazil.
Marcelo BrocchiDepartamento de Genética, Evolução, Microbiologia e Immunologia, Instituto de Biologia, Universidade Estadual de Campinas - UNICAMP, Campinas, São Paulo 13083-862, Brazil.ORCID 0000-0002-3020-531X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Violacein exhibits antitumor activity, indicating potential for future clinical application. However, an efficient delivery system is required for the clinical use of this hydrophobic compound. Effective delivery systems can enhance the solubility and bioavailability of hydrophobic compounds like violacein, facilitating its clinical application for antitumor therapy. Recent studies have demonstrated that outer membrane vesicles (OMVs) can serve as nanocarriers. This article constitutes the first report to present both

Indexed as

Antineoplastic AgentsBacterial Outer MembraneIndolesMelanomaMelanoma, ExperimentalSalmonella entericaAnimalsCell Line, TumorCell SurvivalDrug CarriersMiceAntineoplastic AgentsDrug CarriersIndolesviolaceinantitumordelivery vectorextracellular vesiclesmacrophagesnanocarrierSalmonella enterica Typhimuriumviolacein

Identifiers

PMID40931613
PMCPMC12522090

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.