ReviewWorld journal of psychiatry2025
Polyphenols: A top-down approach to nutrition and depression.
Review in World journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Association between adherence to the Dietary Approaches to Stop Hypertension diet and depression and anxiety severity in the Mashhad Stroke and Heart Atherosclerotic Disorder study population.Public health nutrition · 2026Article
- Anxiety and depression symptoms in relation to body mass index, fruit and vegetable intake, and physical activity among nutrition students in Peru: a cross-sectional study.Frontiers in nutrition · 2026Article
- Exploring the potential of polyphenols in major depression: from molecular function to clinical therapy.Frontiers in nutrition · 2026Review
- Polyphenol Consumption and Its Association with Physical and Mental Health in Adults with Major Depressive Disorder.Nutrients · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Depression is a common psychiatric condition with a considerable influence on global health. Although current pharmacotherapeutic choices are of indisputable relevance, there is sustained interest in natural medicines for treating depressive symptoms. Polyphenols, a class of plant-derived natural compounds, have received attention due to their possible neuroprotective and anti-depressive properties. In this review, we aimed to present the intricate mechanisms through which polyphenols modulate inflammation, neurogenesis, oxidative stress, and the gut microbiota. Consumption of polyphenol-rich diets is emerging as a non-invasive, natural, and cost-effective approach to supporting brain health, with potential influence on depressive symptoms. While there have been promising results, more research is needed to draw solid conclusions regarding the medicinal potential of polyphenols.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.