ArticleFrontiers in nutrition2025
Correlation between changes of amino acid spectrum and alopecia in patients with obesity undergoing bariatric surgery: a prospective cohort study.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: To investigate the association between serum amino acid changes and alopecia in patients with obesity before and after bariatric surgery, and identify risk factors for postoperative alopecia. Methods: This prospective cohort study (ChiCTR2300074104) included patients with obesity undergoing laparoscopic sleeve gastrectomy (LSG), categorized into non-mild alopecia (NM group, Results: Among 67 patients analyzed, LSG significantly decreased serum concentrations of arginine, alanine, threonine, glutamic acid, branched-chain amino acids (valine, isoleucine, leucine), and aromatic amino acids (tyrosine, phenylalanine, tryptophan) ( Conclusion: LSG surgery alters the serum amino acid profile in patients with obesity, and serum leucine concentration at 3 months postoperatively is an influential factor in postoperative alopecia.
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