ArticleFrontiers in nutrition2025
Six weeks of either EPA-rich or DHA-rich Omega-3 supplementation alters submaximal exercise physiology in endurance trained male amateurs.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
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- Food-specific IgG-based elimination diet decreased IL-6, TNF-α, and CGRP and improved symptoms in adults with migraine.Frontiers in nutrition · 2025Trial
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Supplementation with Omega-3 fatty acids such as Docosahexaenoic acid (DHA) and/or Eicosapentaenoic acid (EPA) have been shown to lower submaximal exercise heart rate (HR) and whole-body oxygen consumption along with other positive exercise physiology adaptations. However, the impact of supplementation on exercise physiology is inconsistent. This could be due to existing study heterogeneity, including inconsistent use of EPA or DHA supplements. The current study aimed to investigate if EPA-rich or DHA-rich supplements are equally efficient at modifying physiological responses to submaximal exercise and potentially improving performance. Methods: Fifty-five endurance trained amateurs participated in a submaximal exercise test followed by a 24 km time trial (TT) before and after a six-week supplementation period. Participants were supplemented with either 3 g/day EPA-rich fish oil, DHA-rich algae oil, or a coconut oil placebo. Omega-3 index, submaximal exercising HR, rating of perceived exertion (RPE), respiratory exchange ratio (RER), and TT performance were all assessed. Results: The EPA-rich and DHA-rich supplements significantly increased the Omega-3 index, whereas the placebo supplement had no effect. Statistically significant changes between pre-and post-supplementation were found in submaximal exercise physiology. Both EPA-rich and DHA-rich supplementation lowered submaximal exercising HR (∆ = -4, Conclusion: This study adds further evidence that both EPA and DHA can alter submaximal exercise physiology, but further research is required to determine their effects on exercise performance outcomes.
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