ArticleFrontiers in medicine2025
Triglyceride-glucose index and related parameters in the diagnosis and predictive efficacy for older adults with NAFLD/MASLD: a prospective cohort study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Associations of TyG-related indices with NAFLD-related outcomes: A systematic review and meta-analysis.Medicine · 2026Pooled it
- Triglyceride glucose-body mass index as a practical screening tool for metabolic dysfunction-associated steatotic liver disease in older adults: A community-based cohort study.Asia Pacific journal of clinical nutrition · 2026Article
- The association of the combined triglyceride-glucose and frailty index with chronic liver disease: evidence from the CHARLS study.BMC gastroenterology · 2026Article
- Diagnostic performance of TyG-related indices for MAFLD screening in older adults at moderate altitude: TyG-BMI showed the highest discriminatory ability.BMC gastroenterology · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Non-alcoholic fatty liver disease (NAFLD) affects over 25% of the global population and is associated with numerous comorbidities. Several indices, including the triglyceride-glucose (TyG) index, TyG-waist circumference (TyG-WC), TyG-body mass index (TyG-BMI), and TyG-waist-height ratio (TyG-WHtR), have been strongly associated with NAFLD. However, research on the stratification of hepatic steatosis severity in NAFLD, particularly in older adults, remains limited. This study aimed to investigate the relationship between TyG index and NAFLD in elderly individuals. Methods: This study analyzed physical examination data from 3,954 individuals aged 60 years or older, collected during a 2-year follow-up period at Nan'an General Hospital, Nanqiao Branch. Binary logistic regression and receiver operating characteristic curve analyses were employed to examine the relationship between the TyG index and NAFLD and its various pathological stages. Additionally, the change in the TyG index during follow-up was calculated to assess its predictive significance for NAFLD progression. Results: The TyG, TyG-WC, TyG-BMI, and TyG-WHtR quartiles were grouped for analysis in patients with NAFLD, revealing significant differences in hepatic steatosis severity between the groups ( Conclusion: The TyG index and its related parameters serve as reliable, non-invasive indicators for the diagnosis and progression of NAFLD in elderly populations. Monitoring changes in these indices can improve early detection and management of NAFLD.
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