ArticleOphthalmology science
Bile Acid Metabolism Changes in Patients with a
Article in Ophthalmology science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
11 authors.
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Abstract
Purpose: To compare the plasma metabolic profile of patients with a Design: A case-control study. Participants: A cohort of 30 Dutch patients with Methods: The MxP Quant 500 Kit was used for measuring metabolite concentrations. We fitted a linear regression model with adjustments for age and sex based on the concentration of metabolites in micromolar (micromoles per liter) or on the sums and ratios of metabolites to determine differences between patients and controls. Main Outcome Measures: Plasma concentration of 619 metabolites. Results: Overrepresentation of pathways among metabolites associated strongest to Conclusions: Lipid metabolic alterations and decreased microbiota-related secondary bile acid concentrations indicate significant alterations in gut Financial Disclosures: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
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