Evidence mapPaperPMID 40933856Full record

ArticleNature and science of sleep2025

Ultrasound-Guided Stellate Ganglion Block with Cervicotemporal Myofascial Trigger Point Acupuncture for Insomnia with Comorbid Anxiety and Depression: A Retrospective Observational Study.

Zhenzhen Li, Lifeng Wang, Peilin Cong, Siyu Chen, Jingxuan Wang, He Zhang, Juan Zhao, Guiting Li, Fengmei Jiao, Linyan Li and 5 more

Abstract read
In one paragraph

Article in Nature and science of sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Zhenzhen Li *Anesthesia Insomnia Clinic, Department of Anesthesiology Outpatient Clinic, Shandong Second Provincial General Hospital, Jinan, 250022, People's Republic of China.
Lifeng Wang *Anesthesia Insomnia Clinic, Department of Anesthesiology Outpatient Clinic, Shandong Second Provincial General Hospital, Jinan, 250022, People's Republic of China.
Peilin Cong *Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Translational Research Institute of Brain and Brain-Like Intelligence, Clinical Research Center for Anesthesiology and Perioperative Medicine, Department of Anesthesiology and Perioperative Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, 200434, People's Republic of China.ORCID 0000-0002-4522-0272
Siyu ChenDepartment of Science and Education, Shandong Second Provincial General Hospital, Jinan, 250022, People's Republic of China.
Jingxuan WangDepartment of Pain, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250011, People's Republic of China.
He ZhangAnesthesia Insomnia Clinic, Department of Anesthesiology Outpatient Clinic, Shandong Second Provincial General Hospital, Jinan, 250022, People's Republic of China.
Juan ZhaoAnesthesia Insomnia Clinic, Department of Anesthesiology Outpatient Clinic, Shandong Second Provincial General Hospital, Jinan, 250022, People's Republic of China.
Guiting LiAnesthesia Insomnia Clinic, Department of Anesthesiology Outpatient Clinic, Shandong Second Provincial General Hospital, Jinan, 250022, People's Republic of China.
Fengmei JiaoAnesthesia Insomnia Clinic, Department of Anesthesiology Outpatient Clinic, Shandong Second Provincial General Hospital, Jinan, 250022, People's Republic of China.
Linyan LiAnesthesia Insomnia Clinic, Department of Anesthesiology Outpatient Clinic, Shandong Second Provincial General Hospital, Jinan, 250022, People's Republic of China.
Ruitao WangAnesthesia Insomnia Clinic, Department of Anesthesiology Outpatient Clinic, Shandong Second Provincial General Hospital, Jinan, 250022, People's Republic of China.
Qianqian WuShanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Translational Research Institute of Brain and Brain-Like Intelligence, Clinical Research Center for Anesthesiology and Perioperative Medicine, Department of Anesthesiology and Perioperative Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, 200434, People's Republic of China.
Moxuan GongDepartment of Pain, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200041, People's Republic of China.
Zheping ChenShanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Translational Research Institute of Brain and Brain-Like Intelligence, Clinical Research Center for Anesthesiology and Perioperative Medicine, Department of Anesthesiology and Perioperative Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, 200434, People's Republic of China.ORCID 0009-0000-0677-2894
Yaozhu WangAnesthesia Insomnia Clinic, Department of Anesthesiology Outpatient Clinic, Shandong Second Provincial General Hospital, Jinan, 250022, People's Republic of China.ORCID 0000-0002-4955-4085

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Insomnia is a prevalent sleep-wake disturbance that significantly impairs the quality of life and adversely affects physical and mental health. This study aimed to evaluate the clinical efficacy of ultrasound-guided stellate ganglion block (SGB) combined with acupuncture at cervicotemporal myofascial trigger points (MTrPs) in patients with insomnia accompanied by anxiety and depression. Patients and Methods: This retrospective study included 42 patients diagnosed with insomnia and comorbid anxiety and depression who were treated at the Anesthesia and Sleep Clinic of the Shandong Second Provincial General Hospital between November 2024 and April 2025. All patients received ultrasound-guided SGB combined with acupuncture at cervicotemporal MTrPs. Treatment efficacy was assessed by comparing Pittsburgh Sleep Quality Index (PSQI), Hamilton Anxiety Scale (HAMA), and Hamilton Depression Scale (HAMD) scores before treatment initiation and four weeks after completion of the intervention. Results: Compared with baseline, post-treatment PSQI scores (5.00 ± 2.84 versus 17.10 ± 2.61; mean difference, -12.10; 95% Cl, -12.91 to -11.28; Conclusion: The preliminary study suggests that ultrasound-guided SGB combined with acupuncture at the cervicotemporal MTrPs is an effective, comprehensive intervention for insomnia with comorbid anxiety and depression. The benefits may result from synergistic mechanisms involving autonomic balance regulation, suppression of excessive sympathetic activity, reduction of myofascial tension, and modulation of the sleep-wake cycle. These findings warrant further clinical application and investigation.

Indexed as

acupuncture therapyautonomic nervous system modulationemotional disordersinsomniasleep qualitysympathetic blockade

Identifiers

PMID40933856
PMCPMC12419216

What Socratic holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.