Evidence mapPaperPMID 40933939Full record

ArticleWorld journal of clinical cases2025

Life-course management of gestational diabetes mellitus: A narrative review.

Qing-Jing Luo, Qiang Ni

Abstract read
In one paragraph

Article in World journal of clinical cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Special Issue "Molecular Insight into Gestational Diabetes Mellitus".International journal of molecular sciences · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Qing-Jing LuoWest China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Qiang NiWest China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGestational diabetes mellitus (GDM) has emerged as a global public health challenge, fueled by increasing maternal age, rising obesity rates, and lifestyle shifts. It is linked to substantial short- and long-term health risks for both mothers and their offspring, offering a critical opportunity for intergenerational prevention of metabolic disorders.

aimTo synthesize current evidence on the pathophysiology, diagnosis, management, complications, and individualized treatment strategies of GDM.

methodsWe conducted a narrative review in accordance with PRISMA guidelines. PubMed, Scopus, Web of Science, and EMBASE were searched for English-language articles (2017-2025) using terms such as "GDM", "pregnancy", "insulin resistance", and "maternal outcomes". After removing duplicates, 512 records were screened; 102 full texts were assessed for eligibility, and 55 studies were included based on methodological quality, clinical relevance, and alignment with the review objectives.

resultsGDM results from a complex interplay among progressive insulin resistance, β-cell dysfunction, immune dysregulation, and placental inflammation. Emerging evidence indicates that hyperglycemia before formal diagnosis can impair fetal programming

conclusionGDM requires precision-based, life-course care. Future priorities include early risk detection, biomarker validation, unified diagnosis, and culturally sensitive interventions to improve maternal-child outcomes.

Indexed as

EpigeneticsFetal programmingGestational diabetes mellitusInsulin resistanceLife-course managementPostpartum follow-upPrecision medicinePregnancyPublic healthType 2 diabetes mellitus

Identifiers

PMID40933939
PMCPMC12417949

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.