Evidence mapPaperPMID 40935393Full record

ArticleJournal of microbiology and biotechnology2025

Mitigation of

Seong-Min Hong, Su-Hyun Kim, Jae-Hyuk Lee, Choong-Hwan Lee, Dong-Hyun Kim, Sun Yeou Kim

Abstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A putativeFrontiers in immunology · 2026
    Article
  2. Deciphering the mechanisms by which probioticCurrent research in food science · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Seong-Min HongCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon 21936, Republic of Korea.
Su-Hyun KimDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea.
Jae-Hyuk LeeAmtixBio Co., Ltd., Hanam-si 12925 Republic of Korea.
Choong-Hwan LeeDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea.
Dong-Hyun KimNeurobiota Research Center, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.
Sun Yeou KimCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon 21936, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methylglyoxal (MGO), a reactive byproduct of microbial metabolism, contributes to neurodegeneration and may be further exacerbated by gut dysbiosis. Probiotic strategies that restore microbial balance and barrier integrity thus represent a promising therapeutic approach. In this study, we explored the neuroprotective potential of the probiotic strain

Indexed as

Bifidobacterium longumNeuronsNeuroprotective AgentsProbioticsPyruvaldehydeAnimalsAntioxidantsApoptosisCell LineHeme Oxygenase-1MiceNF-E2-Related Factor 2NF-kappa BReactive Oxygen SpeciesSignal TransductionTryptophanAntioxidantsHeme Oxygenase-1Neuroprotective AgentsNF-E2-Related Factor 2NF-kappa BPyruvaldehydeReactive Oxygen SpeciesTryptophanBifidobacterium longum Z1methylglyoxalN2a cellsneuroprotective effecttryptophan

Identifiers

PMID40935393
PMCPMC12438956

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.