Evidence map›Paper›PMID 40935668›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025

Metallothionein III Mediates Ca

Lyndsie Salvagio, Chen Zhang, Braden E Rue, Nicole Doris, Ci Koehring, Isabella Tyler, Raul Satoshi Vargas, Won Chan Oh, Yan Qin

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lyndsie SalvagioDepartment of Biological Sciences, University of Denver, Denver, Colorado 80210.
Chen ZhangDepartment of Biological Sciences, University of Denver, Denver, Colorado 80210.
Braden E RueDepartment of Biological Sciences, University of Denver, Denver, Colorado 80210.
Nicole DorisDepartment of Biological Sciences, University of Denver, Denver, Colorado 80210.
Ci KoehringDepartment of Biological Sciences, University of Denver, Denver, Colorado 80210.
Isabella TylerDepartment of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado 80045.
Raul Satoshi VargasDepartment of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado 80045.
Won Chan OhDepartment of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado 80045.ORCID 0000-0001-5144-2616
Yan QinDepartment of Biological Sciences, University of Denver, Denver, Colorado 80210 Yan.Qin@du.edu.ORCID 0000-0003-3640-0105

Funding

Serotonergic modulation of excitatory synapse formation and maturation during developmentR01MH124778 · NIMH · UNIVERSITY OF COLORADO DENVER · PI OH, WON CHAN · 2021 to 2025
$1.9M
Regulations of organellar Zn2+ homeostasis and dynamics by TRPML1 in neuronsR01NS110590 · NINDS · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI QIN, YAN · 2019 to 2023
$1.6M
The dual roles of GABA in excitatory synaptic plasticityR21MH137409 · NIMH · UNIVERSITY OF COLORADO DENVER · PI OH, WON CHAN · 2024 to 2025
$429k
A new approach to understanding cognitive disabilities in Down syndromeR21NS133681 · NINDS · UNIVERSITY OF COLORADO DENVER · PI OH, WON CHAN · 2023 to 2023
$429k
NIMH NIH HHS R01 MH124778NIMH NIH HHS R21 MH137409NINDS NIH HHS R01 NS110590NINDS NIH HHS R21 NS133681
6 · The paper itself

Abstract

Zinc is crucial for neuron function, but whether and how labile zinc ion (Zn

Indexed as

CalciumDendritesMetallothioneinNerve Tissue ProteinsZincAnimalsCells, CulturedChlorocebus aethiopsCOS CellsFemaleHeLa CellsHippocampusHumansMaleMetallothionein 3MiceCalciumMetallothioneinMetallothionein 3Mt3 protein, mouseNerve Tissue ProteinsZincdendritic arborizationmetallothionein-3neurite developmentZn2+ spikes

Identifiers

PMID40935668
PMCPMC12528839

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.