Evidence map›Paper›PMID 40935854›Full record

ArticleExperimental & molecular medicine2025

The potential role of hypothalamic POMC

Ju Hwan Yang, Arbi Bahtiar Boedi Iman Halanobis, Eun-Hye Byeon, Na Hyun Park, Sang Won Park, Hyun Joon Kim, Dawon Kang, Deok-Ryong Kim, Jinsung Yang, Eun Sang Choe and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental & molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ju Hwan YangDepartment of Physiology, Institute of Medical Sciences, Gyeongsang National University College of Medicine, Jinju, Republic of Korea.
Arbi Bahtiar Boedi Iman HalanobisDepartment of Physiology, Institute of Medical Sciences, Gyeongsang National University College of Medicine, Jinju, Republic of Korea.
Eun-Hye ByeonDepartment of Physiology, Institute of Medical Sciences, Gyeongsang National University College of Medicine, Jinju, Republic of Korea.
Na Hyun ParkDepartment of Physiology, Institute of Medical Sciences, Gyeongsang National University College of Medicine, Jinju, Republic of Korea.
Sang Won ParkConvergence of Medical Sciences, Gyeongsang National University College of Medicine, Jinju, Republic of Korea.ORCID http://orcid.org/0000-0002-6149-5284
Hyun Joon KimConvergence of Medical Sciences, Gyeongsang National University College of Medicine, Jinju, Republic of Korea.
Dawon KangDepartment of Physiology, Institute of Medical Sciences, Gyeongsang National University College of Medicine, Jinju, Republic of Korea.
Deok-Ryong KimConvergence of Medical Sciences, Gyeongsang National University College of Medicine, Jinju, Republic of Korea.ORCID http://orcid.org/0000-0002-3288-8257
Jinsung YangConvergence of Medical Sciences, Gyeongsang National University College of Medicine, Jinju, Republic of Korea.
Eun Sang ChoeDepartment of Biological Sciences, Pusan National University, Busan, Republic of Korea.
Wanil KimConvergence of Medical Sciences, Gyeongsang National University College of Medicine, Jinju, Republic of Korea. wkim@gnu.ac.kr.
Dong Kun LeeDepartment of Physiology, Institute of Medical Sciences, Gyeongsang National University College of Medicine, Jinju, Republic of Korea. dklee@gnu.ac.kr.ORCID http://orcid.org/0000-0001-9969-0117

Funding

National Research Foundation of Korea (NRF) 2020R1C1C1012561National Research Foundation of Korea (NRF) 2020R1I1A306867013National Research Foundation of Korea (NRF) 2021R1A4A302712212National Research Foundation of Korea (NRF) RS-2023-00219399
6 · The paper itself

Abstract

The major function of primary order neurons in the arcuate nucleus of the hypothalamus is control of energy homeostasis. Among these neurons, proopiomelanocortin (POMC) neurons play a significant role in controlling anorexigenic feeding behavior and upregulating energy expenditure. In addition, transient receptor potential melastatin 2 (TRPM2) is a well-established temperature sensor, but no evidence of regulation of brown adipose tissue (BAT) thermogenesis via POMC

Indexed as

Adipose Tissue, BrownHypothalamusPro-OpiomelanocortinThermogenesisTRPM Cation ChannelsAnimalsMaleMiceMice, Inbred C57BLNeuronsPro-OpiomelanocortinTRPM Cation Channels

Identifiers

PMID40935854
PMCPMC12508090

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.