Evidence map›Paper›PMID 40936787›Full record

ArticleGastroenterology and hepatology from bed to bench2025

Elham Pishgar, Hoda Mahdavi

Abstract read
In one paragraph

Article in Gastroenterology and hepatology from bed to bench, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Elham PishgarColorectal Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Hoda MahdaviDepartment of Radiation Oncology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Given the positive results of some research, this study aimed to explore the relationship between the presence of Background: Epidemiological studies have been conducted to investigate the association between HP infection and CRC. Methods: This cross-sectional study retrieved data from the hospital database, considering inclusion criteria and medical record availability for patients who underwent both endoscopy and colonoscopy and were diagnosed with CRC. Patients were grouped based on tumor grade and location and compared regarding the presence or absence of HP pathogen in endoscopic biopsy direct smears. Results: Data from 241 patients were available, 220 of whom had adenocarcinoma. A statistically significant relationship between tumor differentiation grade and HP positivity was observed (P= 0.001). Each 1-level increase in grade was associated with 2.2 times higher odds of HP positivity. No significant relationships existed in the analysis of tumor location related to HP positivity. Conclusion: In colorectal cancer patients, the presence of the HP pathogen may be linked to a higher likelihood of high-grade colorectal cancers. This finding needs to be explored in screening cohorts.

Indexed as

Colorectal cancerHelicobacter pyloriTumor grade

Identifiers

PMID40936787
PMCPMC12421928

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.