ArticlemBio2025
Human antibody targeting
Abstract read
In one paragraph
Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
24 authors.
Smriti VermaDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-3760-8090
Murat CetinbasDepartment of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Meagan KellyDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Stefania SengerDivision of Pediatric Gastroenterology and Nutrition, Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Christina S FahertyDivision of Pediatric Gastroenterology and Nutrition, Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-3200-161X
Jeshina JanardhananDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Chanchal R WaghDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Taufiqur Rahman BhuiyanInternational Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), Dhaka, Bangladesh.ORCID 0000-0003-3755-4763
Fahima ChowdhuryInternational Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), Dhaka, Bangladesh.
Ashraful Islam KhanInternational Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), Dhaka, Bangladesh.
Aklima AkterInternational Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), Dhaka, Bangladesh.
Richelle C CharlesDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-8881-1849
Jason B HarrisDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Stephen B CalderwoodDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Jens WrammertDivision of Infectious Disease, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0002-1733-4424
Matthew K WaldorDepartment of Microbiology and Immunology, Harvard Medical School, Boston, Massachusetts, USA.
Merrill AspDepartment of Molecular, Cellular and Development Biology, Quantitative Biology Institute, Yale University, New Haven, Connecticut, USA.
Jung-Shen Benny TaiDepartment of Molecular, Cellular and Development Biology, Quantitative Biology Institute, Yale University, New Haven, Connecticut, USA.
Jing YanDepartment of Molecular, Cellular and Development Biology, Quantitative Biology Institute, Yale University, New Haven, Connecticut, USA.
Peng XuLaboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Pavol KováčLaboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Ruslan I SadreyevDepartment of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Firdausi QadriInternational Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), Dhaka, Bangladesh.ORCID 0000-0002-8928-9888
Edward T RyanDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0009-0005-0169-394X
Funding
ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6MImmune Responses to Vibrio cholerae infection and vaccination in HaitiR01AI099243 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HARRIS, JASON B, IVERS, LOUISE C. · 2012 to 2022
$7.9MVibrio cholerae intestinal colonization and vaccine developmentR01AI042347 · NIAID · TUFTS UNIVERSITY BOSTON · PI WALDOR, MATTHEW K · 1998 to 2025
$7.3MTraining program in vaccine development and public healthD43TW005572 · FIC · MASSACHUSETTS GENERAL HOSPITAL · PI QADRI, FIRDAUSI, RYAN, EDWARD T. · 2000 to 2025
$5.4MO-Specific Polysaccharide Responses and CholeraR37AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Edward T. Ryan · 2020 to 2026
$5.1MAntibody mediated protective immunity against choleraR01AI137164 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CHARLES, RICHELLE C, HARRIS, JASON B · 2018 to 2022
$3.9MMolecular Biology and Virulence of CTX PhageR37AI042347 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI WALDOR, MATTHEW K · 2008 to 2017
$3.8MO-Specific Polysaccharide Responses and CholeraR01AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RYAN, EDWARD T. · 2014 to 2018
$3.7MHuman B cell responses to a live attenuated cholera vaccineR01AI137127 · NIAID · EMORY UNIVERSITY · PI WRAMMERT, JENS PETER · 2018 to 2022
$1.9MO-Specific Polysaccharide Responses and CholeraR56AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RYAN, EDWARD T. · 2013 to 2020
$843kHumoral and adaptive immune responses study in Vibrio cholerae infectionK43TW010362 · FIC · INTERNATIONAL CTR/DIARRHOEAL DIS RES · PI BHUIYAN, MD TAUFIQUR RAHMAN · 2016 to 2020
$359kCharles H. Revson Foundation 25-19Damon Runyon Cancer Research Foundation DRG-2446-21FIC NIH HHS D43 TW005572FIC NIH HHS K43 TW010362FIC NIH HHS TW005572FIC NIH HHS TW010362National Institute of Allergy and Infectious Diseases AI042347National Institute of Allergy and Infectious Diseases AI099243National Institute of Allergy and Infectious Diseases AI106878National Institute of Allergy and Infectious Diseases AI137127National Institute of Allergy and Infectious Diseases AI137164National Science Foundation 2438891NIAID NIH HHS R01 AI042347NIAID NIH HHS R01 AI099243NIAID NIH HHS R01 AI106878NIAID NIH HHS R01 AI137127NIAID NIH HHS R01 AI137164NIAID NIH HHS R37 AI042347NIAID NIH HHS R37 AI106878NIAID NIH HHS R56 AI106878NIDDK NIH HHS 5P30DK04561-28NIDDK NIH HHS DK040561NIDDK NIH HHS P30 DK040561Simons Foundation International SFI-LS-ECIAMEE-00006634
Abstract
Antibodies targeting the O-specific polysaccharide (OSP) of
Indexed as
Antibodies, BacterialAntibodies, MonoclonalCholeraO AntigensVibrio cholerae O1Gene Expression ProfilingGene Expression Regulation, BacterialHumansLocomotionMucinsPhenotypeVirulenceAntibodies, BacterialAntibodies, MonoclonalMucinsO Antigensanti-OSP antibodybiofilmmotilitymucintranscriptomic profilingVibrio cholerae
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.