Evidence map›Paper›PMID 40940997›Full record

ArticleCancers2025

Clinical Utility of the EpiSwitch CiRT Test to Guide Immunotherapy Across Solid Tumors: Interim Results from the PROWES Study.

Joe Abdo, Joos Berghausen, Ryan Mathis, Thomas Guiel, Ewan Hunter, Robert Heaton, Alexandre Akoulitchev, Sashi Naidu, Kashyap Patel

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Joe AbdoOxford BioDynamics Inc., 7495 New Horizon Way, STE 110, Frederick, MD 21703, USA.ORCID 0000-0002-1463-9038
Joos BerghausenDepartment of Pharmacology and Physiology, Georgetown University Medical Center, 3900 Reservoir Rd NW, Washington, DC 20057, USA.
Ryan MathisOxford BioDynamics Inc., 7495 New Horizon Way, STE 110, Frederick, MD 21703, USA.
Thomas GuielOxford BioDynamics CLIA Laboratory, 7495 New Horizon Way, STE 110, Frederick, MD 21703, USA.
Ewan HunterOxford BioDynamics Plc., 3140 Rowan Palace, John Smith Drive, Oxford OX4 2WB, UK.
Robert HeatonOxford BioDynamics CLIA Laboratory, 7495 New Horizon Way, STE 110, Frederick, MD 21703, USA.
Alexandre AkoulitchevOxford BioDynamics Plc., 3140 Rowan Palace, John Smith Drive, Oxford OX4 2WB, UK.
Sashi NaiduCarolina Blood & Cancer Care Associates, 1583 Healthcare Drive Rock Hill, Rock Hill, SC 29732, USA.
Kashyap PatelCarolina Blood & Cancer Care Associates, 1583 Healthcare Drive Rock Hill, Rock Hill, SC 29732, USA.

Funding

Pharmacological Sciences Training Program (PSTP)T32GM142520 · NIGMS · GEORGETOWN UNIVERSITY · PI Patrick Alexander Forcelli, Anton Wellstein · 2022 to 2026
$1.3M
NIGMS NIH HHS T32 GM142520
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

3D genome conformationblood-based cancer diagnosticscheckpoint inhibitorsEpiSwitch CiRT assayimmunotherapy responseprecision oncologypredicting checkpoint inhibitor responsereal-world evidence

Identifiers

PMID40940997
PMCPMC12427751

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.