Evidence map›Paper›PMID 40942013›Full record

ReviewMolecules (Basel, Switzerland)2025

Nano-Based Technology in Glioblastoma.

Dorota Bartusik-Aebisher, Izabela Rudy, Karolina Pięta, David Aebisher

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dorota Bartusik-AebisherDepartment of Biochemistry and General Chemistry, Faculty of Medicine, Collegium Medicum, University of Rzeszów, 35-959 Rzeszów, Poland.ORCID 0000-0002-5557-5464
Izabela RudyStudent Scientific Club of Biochemists URCell, Faculty of Medicine, Collegium Medicum, University of Rzeszów, 35-959 Rzeszów, Poland.
Karolina PiętaStudent Scientific Club of Biochemists URCell, Faculty of Medicine, Collegium Medicum, University of Rzeszów, 35-959 Rzeszów, Poland.
David AebisherDepartment of Photomedicine and Physical Chemistry, Faculty of Medicine, Collegium Medicum, University of Rzeszów, 35-959 Rzeszów, Poland.ORCID 0000-0002-2661-6570

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neoplasms of the central nervous system (CNS) constitute a minor fraction of all malignant tumors. CNS accounts for approximately 4% of newly diagnosed oncological cases. Among primary CNS neoplasms, gliomas predominate, comprising nearly 90% of all malignant brain tumors, with Glioblastoma (GBM) representing the most prevalent and aggressive histological subtype. The earliest documented occurrences of GBM date back to the 19th century. Contemporary therapeutic modalities for GBM primarily involve maximal surgical resection, adjuvant radiotherapy, and systemic chemotherapy. However, the intrinsic heterogeneity of GBM poses a formidable obstacle to treatment efficacy. The immunosuppressive tumor microenvironment, coupled with the restrictive nature of the blood-brain barrier (BBB), significantly limits the intratumorally delivery of chemotherapeutic agents. The emergence of nanotechnology in the biomedical domain has been driven by the urgent need to develop more effective and targeted anticancer interventions. Optimizing therapeutic outcomes necessitates the concurrent application of multimodal strategies. This review emphasizes the Nano-Based Technology in GBM.

Indexed as

Brain NeoplasmsGlioblastomaNanotechnologyAnimalsAntineoplastic AgentsBlood-Brain BarrierDrug Delivery SystemsHumansTumor MicroenvironmentAntineoplastic Agentscentral nervous systemglioblastomananotechnology

Identifiers

PMID40942013
PMCPMC12430025

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.