ReviewInternational journal of molecular sciences2025
The Role of Translation-Associated Proteins in p53 Modulation: Mechanisms and Implications.
Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Cross-generational transcriptomic effects of alcohol use disorder in third generation offspring.Scientific reports · 2026Article
- Ribosome plasticity in glioblastoma: a multi-omics framework for future investigation.Frontiers in genetics · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Translation is the final stage of protein synthesis and involves a broad range of proteins-from those directly participating in the process, such as initiation factors and ribosomal components, to those involved in post-translational regulation. Beyond their canonical functions, many of these proteins also influence key signaling pathways, including those regulating cellular stress responses and tumor suppression. This review explores the current knowledge of translation-associated proteins that modulate the tumor-suppressor protein p53. It highlights the roles of ribosomal proteins, stress arising from impaired ribosome biogenesis (nucleolar stress), and various translation-related factors in influencing p53 stability and activity. By integrating findings from diverse studies, this work provides insight into the intricate interplay between translation and p53 signaling, emphasizing its relevance for cellular homeostasis and stress adaptation.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.