ArticleInternational journal of molecular sciences2025
Placental Polycyclic Aromatic Hydrocarbon (PAH) Levels Are Associated with Spontaneous Preterm Birth.
Gwendolynn Hummel, Sohini Banerjee, Vasanta Putluri, Inaara Malick, Grace Johnson, Abu Hena Mostafa Kamal, Chandra Shekar R Ambati, Nagireddy Putluri, Lori Showalter, Cynthia D Shope and 4 more
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
14 authors.
Gwendolynn HummelDepartment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0003-3276-5190 Sohini BanerjeeDepartment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA.
Vasanta PutluriAdvanced Technology Cores, Baylor College of Medicine, Houston, TX 77030, USA.
Inaara MalickDepartment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA.
Grace JohnsonDepartment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA.
Abu Hena Mostafa KamalAdvanced Technology Cores, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0001-6750-0729 Chandra Shekar R AmbatiAdvanced Technology Cores, Baylor College of Medicine, Houston, TX 77030, USA.
Lori ShowalterDepartment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0009-0006-7663-6023 Cynthia D ShopeDepartment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA.
Joseph HaganDepartment of Pediatrics, Division of Neonatology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-3285-2131 Kjersti M AagaardDepartment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA.
Bhagavatula MoorthyDepartment of Pediatrics, Division of Neonatology, Baylor College of Medicine, Houston, TX 77030, USA.
Melissa A SuterDepartment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0001-9130-3311 Funding
Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Martha P Mims · 2007 to 2026
$73.9MProject 5: Pyolytic conversion of PAHs in contaminated sediments into char to eliminate toxicity and enhance soil fertilityP42ES027725 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Nagireddy Putluri · 2020 to 2026
$17.8MTranslational Research Support CoreP30ES030285 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Fernanda Laezza, Cheryl L. Walker · 2019 to 2026
$14.7MGenetics & Genomics Training ProgramT32GM139534 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI GAD SHAULSKY · 2021 to 2026
$4.8MDecoding tumor metabolic and immunologic interactions driving racial disparity in African American patients with bladder cancer.R01CA282282 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Jianjun Gao, Nagireddy Putluri · 2023 to 2026
$2.5MDevelopmental Reprogramming of Prostate Carcinogenesis by BPARC2ES018789 · NIEHS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI WALKER, CHERYL L. · 2009 to 2010
$1.9MRacial and social contextual factors in relation to epigenome and bladder cancer outcome.P20CA284971 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Veronica B. Ajewole, Rayne Helen Rouce · 2023 to 2026
$1.4MNCI NIH HHS P20 CA284971NCI NIH HHS P30 CA125123NCI NIH HHS R01 CA282282NIEHS NIH HHS P30 ES030285NIEHS NIH HHS P42 ES027725NIEHS NIH HHS RC2 ES018789NIGMS NIH HHS T32 GM139534NIH HHS P42ES027725
6 · The paper itselfAbstract
While the cause of preterm birth (PTB) (i.e., delivery before 37 weeks of gestation) is likely multifactorial, ambient exposure to environmental chemicals has been postulated to play a role in its etiology. Our prior studies of exposure to polycyclic aromatic hydrocarbons (PAHs) in pregnancy have shown an increased level of placental PAH-induced bulky DNA adducts with increasing levels of PAH exposures. In this investigation, we hypothesized that higher levels of placental PAHs would be associated with an increased risk of PTB. Using gas chromatography and mass spectrometry (GC-MS/MS), we measured levels of benzo(a)pyrene (BaP), benzo(b)fluoranthene (BbF) and dibenz(a,h)anthracene (DBA) from n = 323 subjects. We found higher levels of BbF in placentae collected from preterm compared with term deliveries (mean 100.3 vs. 84.14 ng/mL,
Indexed as
PlacentaPolycyclic Aromatic HydrocarbonsPremature BirthAdultBenzo(a)pyreneFemaleGestational AgeHumansInfant, NewbornMalePregnancyBenzo(a)pyrenePolycyclic Aromatic Hydrocarbonsenvironmental healthpregnancySuperfund
Identifiers
PMID40943106
PMCPMC12428254
What Socratic holds
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