Evidence mapPaperPMID 40943178Full record

ReviewInternational journal of molecular sciences2025

Stem Cells in Regenerative Medicine: A Journey from Adult Stem Cells to Induced Pluripotent Cells.

Ylenia Della Rocca, Antonella Mazzone, Guya Diletta Marconi, Oriana Trubiani, Jacopo Pizzicannella, Francesca Diomede

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Stem cells in organogenesis and regeneration.Stem cell research & therapy · 2026
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ylenia Della RoccaDepartment of Innovative Technologies in Medicine & Dentistry, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 31, 66100 Chieti, Italy.ORCID 0000-0002-0108-1776
Antonella MazzoneDepartment of Innovative Technologies in Medicine & Dentistry, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 31, 66100 Chieti, Italy.ORCID 0009-0003-7290-0219
Guya Diletta MarconiDepartment of Innovative Technologies in Medicine & Dentistry, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 31, 66100 Chieti, Italy.ORCID 0000-0001-7754-4653
Oriana TrubianiDepartment of Innovative Technologies in Medicine & Dentistry, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 31, 66100 Chieti, Italy.ORCID 0000-0002-7459-4898
Jacopo PizzicannellaDepartment of Engineering and Geology, "G. d'Annunzio" University of Chieti-Pescara, Viale Pindaro, 42, 65127 Pescara, Italy.ORCID 0000-0003-3318-3758
Francesca DiomedeDepartment of Innovative Technologies in Medicine & Dentistry, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 31, 66100 Chieti, Italy.ORCID 0000-0002-0384-6509

Funding

Italian Ministry of University and Research 2022HXMY4PItalian Ministry of University and Research ECS00000041Italian Ministry of University and Research P2022M3KKC
6 · The paper itself

Abstract

Regenerative medicine is the branch of medicine that aims to repair and regenerate damaged tissues and presents promising avenues for addressing a wide range of currently incurable diseases. Regenerative medicine is based on the use of cell therapy with stem cells that can differentiate into differentiated cells of specific tissues. There are various types of stem cells, which are different in potential and derivation. The aim of this review is to summarize the types of stem cells most studied and recently discovered, from adult stem cells to innovative induced pluripotent stem cells (iPSCs), for regenerative medicine purposes. The stem cells involved in the identification of new regenerative therapeutic approaches are analyzed here through a classification based on the tissues' embryonic derivation: stem cells from ectodermal derivation tissues, stem cells from mesodermal derivation tissues, stem cells from endodermal derivation tissues, and iPSCs.

Indexed as

Adult Stem CellsInduced Pluripotent Stem CellsRegenerative MedicineAnimalsCell DifferentiationHumanshuman adult stem cellshuman embryonic developmentiPSCsmolecular biologyregenerative medicine

Identifiers

PMID40943178
PMCPMC12428536

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.