Evidence map›Paper›PMID 40943382›Full record

ReviewInternational journal of molecular sciences2025

A Comprehensive Review of the Bovine Immune Response to Pathogens.

Ana Lesta, Pablo Jesús Marín-García, Lola Llobat

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ana LestaMolecular Mechanisms of Zoonotic Diseases (MMOPS) Research Group, Departamento Producción y Sanidad Animal, Salud Pública y Ciencia y Tecnología de los Alimentos (PASAPTA), Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, 46113 Valencia, Spain.ORCID 0009-0009-4608-0513
Pablo Jesús Marín-GarcíaDepartamento Producción y Sanidad Animal, Salud Pública y Ciencia y Tecnología de los Alimentos (PASAPTA), Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, 46113 Valencia, Spain.ORCID 0000-0001-9593-3476
Lola LlobatMolecular Mechanisms of Zoonotic Diseases (MMOPS) Research Group, Departamento Producción y Sanidad Animal, Salud Pública y Ciencia y Tecnología de los Alimentos (PASAPTA), Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, 46113 Valencia, Spain.ORCID 0000-0002-9806-9174

Funding

Universidad San Pablo CEU GIR24-30Universidad San Pablo CEU ICLINIC24-01Universidad San Pablo CEU IDOC24-06Universidad San Pablo CEU INDI24-38
6 · The paper itself

Abstract

Dairy cattle are constantly exposed to a wide range of pathogens, which can produce substantial economic losses. The maintenance of homeostasis is not only dependent on the intrinsic characteristics of the animals but also on environmental factors such as the productive system, heat stress, and exposure to vectors and contaminated pastures. In this context, the bovine immune system plays a critical role in maintaining health and productivity. This review provides a comprehensive overview of both innate and adaptive responses in cattle, remarking on key components and summarizing the normal immune response against some of the most frequent pathogens in bovines, as well as how these pathogens have developed strategies to evade or modulate the host's immune system. A deeper understanding of these mechanisms is essential for improving therapeutic strategies and disease prevention in livestock production.

Indexed as

Adaptive ImmunityCattle DiseasesHost-Pathogen InteractionsImmunity, InnateAnimalsCattleBos taurusbovineimmune systempathogensresponse

Identifiers

PMID40943382
PMCPMC12429741

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.