Evidence mapPaperPMID 40943553Full record

ArticleInternational journal of molecular sciences2025

The Role of MCM7 and Its Hosted miR-106b-25 Cluster in Renal Cancer Progression.

Katarzyna M Głuchowska, Bartłomiej Hofman

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Katarzyna M GłuchowskaDepartment of Biochemistry and Molecular Biology, Centre of Postgraduate Medical Education, 01-813 Warsaw, Poland.ORCID 0009-0002-8686-774X
Bartłomiej HofmanIndependent Researcher, 00-735 Warsaw, Poland.ORCID 0000-0002-1188-8186

Funding

National Science Centre 2016/21/N/NZ5/00510National Science Centre 2018/28/T/NZ5/00467
6 · The paper itself

Abstract

Renal cancer is among the deadliest human malignancies. MCM7, a cell cycle-regulating protein, is frequently overexpressed in cancers and is associated with hyperproliferation and cancer progression. miR-25-3p, miR-93-5p, and miR-106b-5p form the miR-106b-25 cluster, located within the

Indexed as

Carcinoma, Renal CellKidney NeoplasmsMicroRNAsMinichromosome Maintenance Complex Component 7ApoptosisCaspase 3Caspase 7Cell Line, TumorCell ProliferationDisease ProgressionGene Expression Regulation, NeoplasticHumansCaspase 3Caspase 7MCM7 protein, humanMicroRNAsMinichromosome Maintenance Complex Component 7MIRN106 microRNA, humanMIRN25 microRNA, humanBRMS1Lcancer progressionccRCC (clear cell Renal Cell Carcinoma)MCM7 genemiR-106bmiR-106b-25 clustermiR-25miR-93NFIBrenal cancer

Identifiers

PMID40943553
PMCPMC12429833

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.