Evidence map›Paper›PMID 40943663›Full record

ArticleInternational journal of molecular sciences2025

Breed Varieties of Pigs for Disease Resistance and Susceptibility to Seneca Valley Virus Infection.

Wentao Wang, Fengze Han, Xinmiao He, Shihan Zhao, Ziluo Zou, Ming Tian, Heshu Chen, Saihui Wu, Yan Sun, Yaokun Jiang and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Wentao WangKey Laboratory of Combining Farming and Animal Husbandry, Ministry of Agriculture, Animal Husbandry Research Institute, Heilongjiang Academy of Agricultural Sciences, No. 368 Xuefu Road, Harbin 150086, China.ORCID 0009-0003-6174-3991
Fengze HanCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.ORCID 0009-0004-5668-2351
Xinmiao HeKey Laboratory of Combining Farming and Animal Husbandry, Ministry of Agriculture, Animal Husbandry Research Institute, Heilongjiang Academy of Agricultural Sciences, No. 368 Xuefu Road, Harbin 150086, China.ORCID 0009-0005-7559-4266
Shihan ZhaoCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.ORCID 0009-0009-0976-924X
Ziluo ZouCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.ORCID 0009-0007-2346-3744
Ming TianKey Laboratory of Combining Farming and Animal Husbandry, Ministry of Agriculture, Animal Husbandry Research Institute, Heilongjiang Academy of Agricultural Sciences, No. 368 Xuefu Road, Harbin 150086, China.ORCID 0000-0001-8046-0944
Heshu ChenKey Laboratory of Combining Farming and Animal Husbandry, Ministry of Agriculture, Animal Husbandry Research Institute, Heilongjiang Academy of Agricultural Sciences, No. 368 Xuefu Road, Harbin 150086, China.ORCID 0009-0005-7969-7297
Saihui WuKey Laboratory of Combining Farming and Animal Husbandry, Ministry of Agriculture, Animal Husbandry Research Institute, Heilongjiang Academy of Agricultural Sciences, No. 368 Xuefu Road, Harbin 150086, China.ORCID 0009-0004-6496-9731
Yan SunCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.ORCID 0009-0008-7993-053X
Yaokun JiangCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.ORCID 0009-0009-1080-7610
Meiqin SunCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.
Libing ZhangCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.ORCID 0009-0000-4476-7893
Kunzhi YuCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.ORCID 0009-0003-9270-6464
Yao WangSchool of Life Sciences, Peking University, Beijing 100871, China.
Yaguang TianCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.
Xinpeng JiangCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.ORCID 0000-0003-1128-2157
Di LiuKey Laboratory of Combining Farming and Animal Husbandry, Ministry of Agriculture, Animal Husbandry Research Institute, Heilongjiang Academy of Agricultural Sciences, No. 368 Xuefu Road, Harbin 150086, China.ORCID 0000-0001-5838-0219

Funding

Heilongjiang province agricultural science and technology innovation leapfrog project (Grant number:CX22JQ03), Heilongjiang Natural Science Foundation for Distinguished Young Scholars (number :JQ2024C004),National System of Modern Agricultural Industry Te CARS-35 CX22JQ03 JQ2024C004 31902169
6 · The paper itself

Abstract

In recent years, outbreaks of Seneca Valley virus (SVV) in pig farms have raised concerns about disease resistance in different pig breeds. Min pigs are an excellent local pig breed in China, but the breed's strong disease resistance mechanism has not been clearly investigated. In this study, Min pigs and Landrace pigs were challenged with SVV, and the differences in pathogenicity between SVV-infected Min and Landrace pigs were evaluated in terms of production performance, survival rate, immune cell activity, pathological changes, viral titer, and cytokine expression. The results show that the mortality rate in Min pigs was significantly lower than that in Landrace pigs without substantial weight loss. The copy number of SVV RNA in the intestinal mucosa of Min pigs was lower than that in Landrace pigs. Additionally, the IgA and IgG titers in Min pigs were higher than those in Landrace pigs. Both the absolute number and percentage of M1 macrophages were elevated in Min pigs relative to Landrace pigs. This study is the first to identify differences in macrophage activity between SVV-infected Min pigs and Landrace pigs. The presented results indicate the potential research value of studying innate immunity differences in disease resistance between pig breeds.

Indexed as

Disease ResistancePicornaviridaePicornaviridae InfectionsSwine DiseasesAnimalsAntibodies, ViralBreedingCytokinesDisease SusceptibilityImmunity, InnateMacrophagesSwineAntibodies, ViralCytokinesdisease resistancemacrophagesMin pigpig breedsseneca valley virus (SVV)

Identifiers

PMID40943663
PMCPMC12429855

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.