Evidence map›Paper›PMID 40944120›Full record

Trial reportNutrients2025

Targeted Microbial Shifts and Metabolite Profiles Were Associated with Clinical Response to an Anti-Inflammatory Diet in Osteoarthritis.

Marta Sala-Climent, Kevin Bu, Roxana Coras, Martha Cedeno, Simone Zuffa, Jessica Murillo-Saich, Helena Mannochio-Russo, Celeste Allaband, Michal K Hose, Anna Quan and 11 more

Registry-linked trialAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07713940 (Effect of Anti-inflammatory Diet in Systemic Lupus Erythematous), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07713940 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Anti-inflammatory Diet in Systemic Lupus Erythematous

TypeinterventionalSponsorUniversity of California, San DiegoRan2026 to 2029Enrolled36ConditionsSystemic Lupus Erthematosus (SLE)Armsanti-inflammatory diet
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. The gut-joint axis in osteoarthritis.Nature reviews. Rheumatology · 2026
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Marta Sala-ClimentDepartment of Medicine, School of Medicine, University of California San Diego, San Diego, CA 92093, USA.ORCID 0000-0003-4583-4562
Kevin BuDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-9030-8062
Roxana CorasDepartment of Medicine, School of Medicine, University of California San Diego, San Diego, CA 92093, USA.ORCID 0000-0001-9547-218X
Martha CedenoDepartment of Medicine, School of Medicine, University of California San Diego, San Diego, CA 92093, USA.
Simone ZuffaSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA 92093, USA.ORCID 0000-0001-7237-3402
Jessica Murillo-SaichDepartment of Medicine, School of Medicine, University of California San Diego, San Diego, CA 92093, USA.ORCID 0000-0002-1169-2888
Helena Mannochio-RussoSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA 92093, USA.ORCID 0000-0002-4961-2353
Celeste AllabandDepartment of Pediatrics, School of Medicine, University of California San Diego, San Diego, CA 92093, USA.
Michal K HoseVA San Diego Healthcare System, San Diego, CA 92161, USA.ORCID 0000-0003-0742-0588
Anna QuanVA San Diego Healthcare System, San Diego, CA 92161, USA.
Soo-In ChoiDepartment of Medicine, School of Medicine, University of California San Diego, San Diego, CA 92093, USA.
Katherine NguyenDepartment of Medicine, School of Medicine, University of California San Diego, San Diego, CA 92093, USA.
Shahrokh GolshanDepartment of Psychiatry, School of Medicine, University of California San Diego, San Diego, CA 92093, USA.
Rebecca B BlankMedicine and Rheumatology, NYU Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-6292-6947
Tiffany HoltDepartment of Psychiatry, School of Medicine, University of California San Diego, San Diego, CA 92093, USA.ORCID 0009-0009-8488-4547
Nancy E LaneMedicine and Rheumatology, UC Davis Health, Sacramento, CA 95817, USA.
Rob KnightDepartment of Pediatrics, School of Medicine, University of California San Diego, San Diego, CA 92093, USA.
Jose ScherMedicine and Rheumatology, NYU Grossman School of Medicine, New York, NY 10016, USA.
Pieter DorresteinSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA 92093, USA.
Jose ClementeDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Monica GumaDepartment of Medicine, School of Medicine, University of California San Diego, San Diego, CA 92093, USA.

Funding

Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2025 to 2025
$9.2M
The Study of Muscle, Mobility and Aging with Knee OAR01AG070647 · UNIVERSITY OF CALIFORNIA AT DAVIS · 2025 to 2025
$458k
Rheumatic Diseases Research Training GrantT32AR064194 · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2025 to 2025
$280k
Krupp Endowed Fund NANCATS NIH HHS UL1 TR004419NIAMS NIH HHS T32 AR064194NIA NIH HHS R01 AG070647NIH HHS T32 OD017863
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DietGastrointestinal MicrobiomeMetabolomeOsteoarthritis, KneeAgedFecesFemaleHumansMaleMiddle AgedPilot ProjectsSalivaTreatment Outcomeanti-inflammatory dietmetabolomemicrobiomemicrobiome–metabolome interactionsnutrition interventionosteoarthritis

Identifiers

PMID40944120
PMCPMC12430150

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.