Improvement Effect and Mechanism of Hydroxytyrosol on Skin Aging Induced Advanced Glycation End Products.

Rui Fan, Yuxin Ma, Meng Sun, Haohao Zhang, Yaxin Han, Junbo Wang, Wenli Zhu, Zhaofeng Zhang

Abstract read

In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Hydroxytyrosol Improves UV-Induced Skin Photoaging via PI3K-AKT/MAPK/JAK-STAT and NF-κB Pathways: Insights From Keratinocytes and In Vivo Validation.Phytotherapy research : PTR · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rui FanDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Haidian District, Beijing 100191, China.

Yuxin MaDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Haidian District, Beijing 100191, China.ORCID 0000-0001-9010-3895

Meng SunDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Haidian District, Beijing 100191, China.

Haohao ZhangDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Haidian District, Beijing 100191, China.

Yaxin HanDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Haidian District, Beijing 100191, China.

Junbo WangDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Haidian District, Beijing 100191, China.

Wenli ZhuDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Haidian District, Beijing 100191, China.ORCID 0000-0002-5028-6639

Zhaofeng ZhangDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Haidian District, Beijing 100191, China.ORCID 0000-0002-9751-1549

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AntioxidantsGlycation End Products, AdvancedPhenylethyl AlcoholSkin AgingAnimalsIleumInterleukin-6MaleMiceMice, Inbred C57BLOccludinOxidative StressSkinSuperoxide Dismutase3,4-dihydroxyphenylethanolAntioxidantsGlycation End Products, AdvancedInterleukin-6OccludinPhenylethyl AlcoholSuperoxide Dismutaseadvanced glycation end productshydroxytyrosolinflammatory responseoxidativeskin aging

Identifiers

PMID40944206

DOI10.3390/nu17172810

PMCPMC12430433

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.