Evidence map›Paper›PMID 40944444›Full record

ArticleAllergy2026

Adherence to Mediterranean Diet During Pregnancy, Breastfeeding, and Development of Food Allergy in the Offspring: Results From the MEDALLION Cohort Study.

Emilia Vassilopoulou, Calliope Karastogiannidou, Anna Comotti, Carlo Agostoni, Myrto-Kalliopi Maragkou, Nikolaos G Papadopoulos, Maria Pasioti, Maria Lithoxopoulou, Gavriela Feketea, Sophia Tsabouri and 2 more

Abstract read
In one paragraph

Article in Allergy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Emilia VassilopoulouDepartment of Nutritional Sciences and Dietetics, School of Health Sciences, International Hellenic University, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-2665-5908
Calliope KarastogiannidouDepartment of Nutritional Sciences and Dietetics, School of Health Sciences, International Hellenic University, Thessaloniki, Greece.ORCID https://orcid.org/0000-0001-6505-5879
Anna ComottiOccupational Health Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.ORCID https://orcid.org/0009-0008-4058-8992
Carlo AgostoniDepartment of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.ORCID https://orcid.org/0000-0002-5006-0832
Myrto-Kalliopi MaragkouDepartment of Nutritional Sciences and Dietetics, School of Health Sciences, International Hellenic University, Thessaloniki, Greece.ORCID https://orcid.org/0009-0009-9034-116X
Nikolaos G PapadopoulosAllergy Department, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Athens, Greece.ORCID https://orcid.org/0000-0002-4448-3468
Maria PasiotiAllergy Department, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Athens, Greece.ORCID https://orcid.org/0000-0001-6658-4828
Maria Lithoxopoulou2nd Department of Neonatology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-6072-2764
Gavriela FeketeaDepartment of Pharmacology, "Luliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.ORCID https://orcid.org/0000-0001-9026-2597
Sophia TsabouriDepartment of Pediatrics, School of Medicine, University of Ioannina, Ioannina, Greece.ORCID https://orcid.org/0000-0001-7584-5401
Gregorio Paolo MilaniDepartment of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.ORCID https://orcid.org/0000-0003-3829-4254
Carina VenterSection of Allergy & Immunology, Department of Pediatrics, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado, USA.ORCID https://orcid.org/0000-0002-7473-5355

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevention is a key strategy for reducing the burden of food allergies (FA). The maternal diet during pregnancy and breastfeeding is increasingly recognized as a factor contributing to FA risk.

methodsWe analyzed data from a sub-cohort of the MEDALLION study to evaluate the association between maternal adherence to the Mediterranean Diet (MedDiet) and the development of FA in offsprings. Maternal dietary intake during pregnancy and lactation was assessed using a validated scale, i.e., the MedDiet Score, along with individual food group consumption. Multiple logistic regression models were performed.

resultsA total of 430 mother-offspring dyads were included in the analysis. Higher maternal adherence to the MedDiet was associated with reduced odds of FA in offspring during both pregnancy (adjusted OR 0.94, 95% CI 0.89-1.00) and lactation (adjusted OR 0.94, 95% CI 0.88-1.00). Increased weekly consumption of fruits and full-fat dairy products during pregnancy, and vegetables during breastfeeding, was associated with reduced likelihood of FA in the offspring. Conversely, higher intake of poultry and red meat (> 3 servings/week) during both periods, and fish consumption during pregnancy (> 1 serving/week), were associated with increased odds of FA.

conclusionsThis study points out that the MedDiet and, especially, some specific components, such as fruits, vegetables, and full-fat dairy products, may contribute to lowering the risk of FA in infants, whereas a higher intake of poultry, red meat, and fish may increase it. These findings support the potential of maternal nutrition to reduce childhood FA.

Indexed as

Breast FeedingDiet, MediterraneanFood HypersensitivityPatient CompliancePrenatal Exposure Delayed EffectsAdultCohort StudiesFemaleHumansInfantInfant, NewbornMaleMaternal Nutritional Physiological PhenomenaPregnancyallergy preventiondietary patternsfood allergyfruitfull‐fat dairyinfant healthmaternal dietMediterranean diettraditional dietvegetables

Identifiers

PMID40944444
PMCPMC12862521

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.