Evidence map›Paper›PMID 40944762›Full record

ArticleMikrochimica acta2025

Smartphone-based colorimetric detection of urease activity in dental plaque for point-of-care screening of Helicobacter pylori infection.

Yuhan Wang, Ping Zhang, Chuxian Zhou, Zicong Zheng, Qiang Quan, Guangbo He, Hening Zhai, Qifang Song, Xiaoli Zhang, Heng Li and 6 more

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yuhan Wang *Guangdong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
Ping Zhang *Center of Clinical Laboratory, The First Affiliated Hospital, Jinan University, Guangzhou, 510632, China.
Chuxian Zhou *Guangdong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
Zicong Zheng *Guangdong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
Qiang Quan *Research Center of Cancer Diagnosis and Therapy, Department of Oncology, the First Affiliated Hospital, Jinan University, Guangzhou, 510632, China.
Guangbo HeGuangdong Zhongxin Biotech Limited, Guangzhou, 510000, China.
Hening ZhaiEndoscopy Center, The First Affiliated Hospital, Jinan University, Guangzhou, 510632, China.
Qifang SongGuangdong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
Xiaoli ZhangGuangdong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
Heng LiDepartment of Clinical Laboratory Medicine, Guangdong Provincial People's Hospital, Southern Medical University, Guangzhou, 510000, China.
Lanhuan PengDepartment of Clinical Laboratory Medicine, Guangdong Provincial People's Hospital, Southern Medical University, Guangzhou, 510000, China.
Yuqin LiaoDepartment of Clinical Laboratory Medicine, Guangdong Provincial People's Hospital, Southern Medical University, Guangzhou, 510000, China.
Wei FangDepartment of Clinical Laboratory Medicine, Guangdong Provincial People's Hospital, Southern Medical University, Guangzhou, 510000, China. fangwei@gdph.org.cn.
Minmin LiCenter of Clinical Laboratory, The First Affiliated Hospital, Jinan University, Guangzhou, 510632, China. limm269@126.com.
Jiajie LiangGuangdong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China. 631101522@qq.com.
Yong TangGuangdong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China. tyjaq7926@163.com.

Funding

Fundamental Research Funds for the Central Universities 21625329Fundamental Research Funds for the Central Universities (21625329), Guangzhou Science and Technology Program Project 2025B01J0005Guangdong Provincial Clinical Research Center for Laboratory Medicine 2023B110008Medical Scientific Research Foundation of Guangdong Province A2023493National Natural Science Foundation of China 32301266Outstanding Innovative Talents Cultivation Funded Programs for Doctoral Students of Jinan University 2023CXB014Young Talents Support Program - Seedling Cultivation Program (Class C) at the College of Life Science and Technology, Jinan University 2025-010C
6 · The paper itself

Abstract

Helicobacter pylori (H. pylori) is a major pathogen associated with gastric ulcers and gastric cancer, infecting approximately half of the global population. Therefore, developing sensitive, rapid, and cost-effective detection methods for H. pylori is critical for public health. We developed an innovative microscale colorimetric microsensor integrated with smartphone ambient-light sensors for portable, on-site quantification of H. pylori-associated urease activity in dental plaque. This low-cost device (< $ 5 fabrication) employs 3D-printed components and a custom app to measure transmittance changes from urease-catalyzed urea hydrolysis with phenol red, achieving a robust correlation with commercial microplate reader absorbance (R

Indexed as

ColorimetryDental PlaqueHelicobacter InfectionsHelicobacter pyloriPoint-of-Care TestingSmartphoneUreaseHumansLimit of DetectionUreaseDental plaqueHelicobacter pyloriOn-site detectionSmartphone-based colorimetric microsensorUrease

Identifiers

PMID40944762

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.