Evidence map›Paper›PMID 40944877›Full record

ArticleAbdominal radiology (New York)2026

Detecting decompensation in cirrhotic patients with varying ascitic volumes using magnetic resonance elastography.

Ziqing Sun, Mengjiao Duan, Mengyue Huang, Feifei Yao, Xiaopan Zhang, Yong Zhang, Kaiyu Wang, Jingjing Liu

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In one paragraph

Article in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Ziqing SunDepartment of MR Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Mengjiao DuanDepartment of MR Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Mengyue HuangDepartment of MR Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Feifei YaoDepartment of MR Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xiaopan ZhangDepartment of MR Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yong ZhangDepartment of MR Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Kaiyu WangMR Research China, GE Healthcare, Beijing, China.
Jingjing LiuDepartment of MR Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. liujingjing198631@126.com.

Funding

Medical Science and Technology Project of Henan Province, China SBGJ202102111
6 · The paper itself

Abstract

purposeThis study aims to detect decompensation in cirrhotic patients with varying volumes of ascites using magnetic resonance elastography (MRE).

methodsWe prospectively reviewed 70 patients with liver cirrhosis who underwent 3D MRE and gadoxetic acid-enhanced magnetic resonance imaging (MRI). Patients were categorized into three groups based on clinical information and ascitic volume: compensated cirrhosis with no or minimal ascites (Group A, n = 30), decompensated cirrhosis with no or minimal ascites (Group B, n = 21), and decompensated cirrhosis with massive ascites (Group C, n = 19). Laboratory indicators were collected, and the Model for End-Stage Liver Disease (MELD) score was calculated. Liver shear stiffness (LSS) and relative liver enhancement (RLE) were measured and compared among the three groups. Receiver operating characteristic (ROC) curve analysis assessed the role of LSS in detecting decompensated cirrhosis with no or minimal ascites. Multivariable logistic regression analysis identified factors associated with this condition.

resultsThe LSS in Group A (3.68 ± 0.20 kPa) was significantly lower than in Group B (5.95 ± 0.50 kPa) and Group C (6.27 ± 0.68 kPa) (both p < 0.001). The RLE in Group A (74.6%±4.5%) was significantly higher than in Group B (58.2%±5.1%) (p = 0.035) and Group C (43.5%±3.3%) (p < 0.001). ROC analysis indicated that LSS effectively differentiates between Group A and Group B (area under the ROC curve is 0.84, 95% confidence interval [CI]: 0.73-0.95). Multivariable analysis identified LSS as an independent risk factor for decompensated cirrhosis with no or minimal ascites.

conclusionMRE is a valuable tool for noninvasively guiding decompensation risk stratification in patients with varying volumes of ascites, particularly those with no or minimal ascites.

Indexed as

AscitesElasticity Imaging TechniquesLiver CirrhosisMagnetic Resonance ImagingAdultAgedContrast MediaFemaleGadolinium DTPAHumansImaging, Three-DimensionalMaleMiddle AgedProspective StudiesContrast MediaGadolinium DTPAgadolinium ethoxybenzyl DTPAAscitesDecompensationLiver cirrhosisLiver shear stiffnessMagnetic resonance elastography

Identifiers

PMID40944877

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.