Evidence map›Paper›PMID 40945336›Full record

ArticlePoultry science2025

Study on anti-fatigue effect and mechanism of iron source combined with Angelica sinensis and Agrimonia pilosa on pigeons under exercise stress.

Chong Ning, Wei Bu, Xiangbei Meng, Huiyu Li, Xinyu Zhang, Yang Tang, Fengqing Hu, Shan Wang, Chang Tan, Chongting Guo and 2 more

Abstract read
In one paragraph

Article in Poultry science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Effect ofAnimals : an open access journal from MDPI · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chong NingCollege of Light Industry, Liaoning University, No. 66, Chongshan Middle Road, Shenyang, 110036, Liaoning, China.
Wei BuCollege of Light Industry, Liaoning University, No. 66, Chongshan Middle Road, Shenyang, 110036, Liaoning, China.
Xiangbei MengCollege of Light Industry, Liaoning University, No. 66, Chongshan Middle Road, Shenyang, 110036, Liaoning, China.
Huiyu LiCollege of Light Industry, Liaoning University, No. 66, Chongshan Middle Road, Shenyang, 110036, Liaoning, China.
Xinyu ZhangCollege of Light Industry, Liaoning University, No. 66, Chongshan Middle Road, Shenyang, 110036, Liaoning, China.
Yang TangCollege of Light Industry, Liaoning University, No. 66, Chongshan Middle Road, Shenyang, 110036, Liaoning, China.
Fengqing HuCollege of Light Industry, Liaoning University, No. 66, Chongshan Middle Road, Shenyang, 110036, Liaoning, China.
Shan WangCollege of Light Industry, Liaoning University, No. 66, Chongshan Middle Road, Shenyang, 110036, Liaoning, China.
Chang TanCollege of Light Industry, Liaoning University, No. 66, Chongshan Middle Road, Shenyang, 110036, Liaoning, China.
Chongting GuoCollege of Light Industry, Liaoning University, No. 66, Chongshan Middle Road, Shenyang, 110036, Liaoning, China.
Yixian LiuLiaoning University of Traditional Chinese Medicine, No. 79, Chongshan East Road, Shenyang, 110847, Liaoning, China. Electronic address: 2522129236@qq.com.
Weixuan LiCollege of Light Industry, Liaoning University, No. 66, Chongshan Middle Road, Shenyang, 110036, Liaoning, China. Electronic address: liweixuan@lnu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the therapeutic effects of sex-specific iron supplementation combined with Angelica sinensis and Agrimonia pilosa on fatigue in pigeons. In Trial 1, 70 pigeons (35 males and 35 females) were randomly divided into seven groups and fed diets supplemented with 100 or 150 mg/kg of ferrous lactate, ferrous gluconate, or ferrous fumarate for 28 days. Blood biochemical indices were monitored weekly to identify the optimal iron source for each sex. The results indicated that female pigeons responded best to 150 mg/kg ferrous lactate, whereas male pigeons responded best to 150 mg/kg ferrous gluconate. In Trial 2, 30 pigeons (15 males and 15 females) were randomly assigned to three groups: control (basal diet), low-dose (3 g/kg A. sinensis: A. pilosa = 1:1 plus sex-specific iron), and high-dose (6 g/kg plus sex-specific iron). Blood samples were collected before supplementation, after 28 days, immediately post-exercise, and after 1 h recovery. Combined nutritional intervention mitigated the accumulation of blood urea nitrogen (BUN) and blood lactic acid (BLA), decreased lactate dehydrogenase (LDH) activity, decreased creatine kinase (CK) release into the bloodstream, reduced malondialdehyde (MDA) levels, enhanced total antioxidant activity (T-AOC) in the serum, and upregulated post-exercise antioxidant capacity in pigeons, ultimately enhancing exercise endurance. This approach shows promise as a sustainable strategy for treating pigeon fatigue.

Indexed as

AgrimoniaAngelica sinensisColumbidaeFatigueIronPhysical Conditioning, AnimalAnimal FeedAnimalsDietDietary SupplementsDose-Response Relationship, DrugFemaleMaleRandom AllocationIronAgrimonia pilosaAngelica sinensisExercise fatigueIron sourcePigeons

Identifiers

PMID40945336
PMCPMC12683127

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.