Evidence map›Paper›PMID 40945428›Full record

ArticleJACC. Advances2025

A Randomized Trial of a Resilience-Building Intervention in Adult Outpatients With Congenital Heart Disease: Feasibility and Efficacy.

Jill M Steiner, Arisa Rei Marshall, Lyndia Brumback, Yixuan Connie Zhang, Thomas M Glenn, Adrienne H Kovacs, Karen K Stout, Chris T Longenecker, Joyce P Yi-Frazier, Abby R Rosenberg

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04738474 (Assessing and Promoting Resilience in Patients With Adult Congenital Heart Disease), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04738474 nacompletednot on this map

Assessing and Promoting Resilience in Patients With Adult Congenital Heart Disease

TypeinterventionalSponsorUniversity of WashingtonRan2023 to 2024Enrolled78ConditionsCongenital Heart DiseaseArmsPromoting Resilience in Stress Management (PRISM), Usual Care
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jill M SteinerDivision of Cardiology, Department of Medicine & Cambia Palliative Care Center of Excellence, University of Washington, Seattle, Washington, USA. Electronic address: jills8@uw.edu.
Arisa Rei MarshallDivision of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, USA.
Lyndia BrumbackDepartment of Biostatistics, University of Washington, Seattle, Washington, USA.
Yixuan Connie ZhangDepartment of Biostatistics, University of Washington, Seattle, Washington, USA.
Thomas M GlennDivision of Cardiology, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA.
Adrienne H KovacsEquilibria Psychological Health, Toronto, Ontario, Canada.
Karen K StoutDivision of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, USA.
Chris T LongeneckerDivision of Cardiology and Department of Global Health, University of Washington, Seattle, Washington, USA.
Joyce P Yi-FrazierDepartment of Supportive Oncology, Dana-Farber Cancer Institute, Department of Pediatrics, Boston Children's Hospital & Harvard Medical School, Boston, Massachusetts, USA.
Abby R RosenbergDepartment of Supportive Oncology, Dana-Farber Cancer Institute, Department of Pediatrics, Boston Children's Hospital & Harvard Medical School, Boston, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInterventions are needed to address growing concerns regarding poor psychosocial and mental health in adult congenital heart disease (ACHD). Strengthening patients' resilience is one proposed pathway, given its ability to improve quality of life in other patient populations.

objectivesThe objective of this study was to evaluate feasibility and efficacy of a resilience-building intervention in ACHD.

methodsWe conducted a clinical trial of outpatients with moderate or complex ACHD, randomized to receive a cognitive-behavioral intervention (Promoting Resilience in Stress Management [PRISM]) vs usual care. Participants completed surveys at randomization and 3 months. We evaluated feasibility using enrollment and retention rates. We evaluated PRISM's effect on the primary outcome (change in self-reported resilience) and exploratory outcomes using linear regression adjusted for baseline measurement.

resultsWe enrolled 78 patients from March 2023 to April 2024. Patients were randomized to treatment (PRISM; n = 40, age 36 ± 11 years; 50% female; 58% self-reported White race/ethnicity) vs control (n = 38, age 40 ± 12 years; 74% female; 79% White). Over three-quarters of participants randomized to treatment completed PRISM (80%) and follow-up measures. Of controls, 35/38 (92%) completed follow-up measures. Resilience scores at 3 months were higher in the treatment group (n = 30, 30.1 ± 8.1) compared to control (n = 35, 28.7 ± 5.8); this difference was not statistically significant. Mean quality of life at follow-up was significantly higher in the treatment group (79 ± 14 vs 73 ± 14; 95% CI: 0.8-12.7; P = 0.03). Program feedback was positive.

conclusionsThis study demonstrates intervention feasibility with modifications. Although we did not demonstrate efficacy, participants were engaged and provided valuable feedback, suggesting value in ACHD. (Assessing and Promoting Resilience in Patients With Adult Congenital Heart Disease [PRISMACHD]; NCT04738474).

Indexed as

clinical trialcognitive-behavioral interventioncongenital heart diseasequality of liferesilience

Identifiers

PMID40945428
PMCPMC12791846

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.