Evidence map›Paper›PMID 40946007›Full record

ReviewSeminars in perinatology2025

Interventions to address inequities in infant mortality and morbidity in the NICU and beyond: A focus on the mother-infant dyad.

Mattie F Wolf, Diana Montoya-Williams, Michelle-Marie Peña

Abstract readReview
In one paragraph

Review in Seminars in perinatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mattie F WolfDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA. Electronic address: mfeasel@emory.edu.
Diana Montoya-WilliamsDepartment of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Michelle-Marie PeñaDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA.

Funding

Translation CoreP2CES033430 · NIEHS · EMORY UNIVERSITY · PI NSEDU OBOT WITHERSPOON · 2022 to 2026
$5.3M
Emory University BIRCWH ProgramK12HD085850 · NICHD · EMORY UNIVERSITY · PI OFOTOKUN, IGHOVWERHA, STERK, CLAIRE E · 2015 to 2023
$4.4M
Microbiome, Environment, and Neurodevelopmental Delay (MEND)P50ES026071 · NIEHS · EMORY UNIVERSITY · PI MCCAULEY, LINDA A. · 2015 to 2018
$3.3M
Pilot Administrative Core - Center for the Study of Symptom Science, Metabolomics and Multiple Chronic ConditionsP30NR018090 · NINR · EMORY UNIVERSITY · PI HOLSTAD, MARCIA MCDONNELL · 2018 to 2022
$3.2M
Pediatric and Reproductive Environmental Health Scholars Southeastern Environmental Exposures and Disparities (PREHS SEED) ProgramK12ES033593 · NIEHS · EMORY UNIVERSITY · PI Linda A. McCauley · 2022 to 2026
$2.4M
Maternal Resilience to Stress, Neonatal Outcomes, and Racial/Ethnic Health DisparitiesK23HD102526 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI MONTOYA-WILLIAMS, DIANA C · 2021 to 2025
$793k
NICHD NIH HHS K12 HD085850NICHD NIH HHS K23 HD102526NIEHS NIH HHS K12 ES033593NIEHS NIH HHS P2C ES033430NIEHS NIH HHS P50 ES026071NINR NIH HHS P30 NR018090
6 · The paper itself

Abstract

In 2022, United States infant mortality increased for the first time in over 20 years, driven largely by deaths due to maternal complications and preterm birth, and highlighted significant racial/ethnic and socioeconomic inequities in both infant mortality and morbidities. This underscores the relationship between maternal and infant health outcomes. This article presents a framework for understanding the mother-infant dyad using an adaptation of the socio-ecological model and focuses on patient and family factors, provider and healthcare system factors, community factors, and policy and societal factors that perpetuate inequities in infant outcomes. The neonatal intensive care unit (NICU) is a driver of inequities, but also provides critical, yet underutilized, opportunities for intervention. Strategies to promote physical, emotional, social, and financial well-being of mothers and infants include NICU-based lactation and mental health support, culturally responsive care, screening for social determinants of health, and engagement of families in care and quality improvement. Beyond the NICU, broader structural and policy changes are essential, including equitable access to risk-appropriate care, paid family leave, comprehensive health insurance, and investments in community partnerships. Addressing these drivers of inequity through coordinated healthcare, policy, and community action can better support the mother-infant dyad and improve the well-being of all families.

Indexed as

Healthcare DisparitiesInfant MortalityIntensive Care Units, NeonatalMother-Child RelationsMothersFemaleHumansInfantInfant, NewbornInfant, PrematurePregnancySocial Determinants of HealthSocioeconomic FactorsUnited StatesInfant mortalityMother infant dyadNeonatal intensive care unitNICU

Identifiers

PMID40946007
PMCPMC12499859

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.