Evidence map›Paper›PMID 40946303›Full record

ArticleAnnals of medicine2025

The impact of diet and lifestyle-related oxidative stress on asthma outcomes: a longitudinal NHANES analysis.

Liling Zeng, Rundong Qin, Tong Zhou, Qiurong Hu, Xu Shi, Wanjun Wang, Jing Li

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PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liling ZengDepartment of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Rundong QinDepartment of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Tong ZhouDepartment of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Qiurong HuDepartment of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xu ShiDepartment of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Wanjun WangDepartment of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.ORCID 0000-0003-1770-2693
Jing LiDepartment of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOxidative stress is known to play a key role in the progression of asthma. The Oxidative Balance Score (OBS), derived from an analysis of diet and lifestyle choices, provides a measure of the body's oxidative stress levels. This study aims to investigate the clinical relevance of OBS in asthma.

methodsThe study included National Health and Nutrition Examination Survey (NHANES) data from 10,038 individuals between the years 2007 and 2018. We assessed associations of asthma prevalence with the OBS, Dietary Oxidative Balance Score (DOBS), and Lifestyle Oxidative Balance Score (LOBS) using logistic regression and restricted cubic spline (RCS) analyses. Lung function was evaluated through correlation analysis. The Cox proportional hazards models were employed to assess all-cause and cardiovascular-specific mortality by OBS components. Subgroup and interaction analyses were conducted to examine heterogeneity and to validate the findings.

resultsAfter adjusting for confounders, higher OBS [OR = 0.98 (0.97, 0.99),

conclusionOur findings suggest that an antioxidant-rich diet and lifestyle may lower the risk of developing asthma and improve the prognosis for individuals with asthma.

Indexed as

AsthmaDietLife StyleOxidative StressAdultFemaleHumansLongitudinal StudiesMaleMiddle AgedNutrition SurveysPrevalenceRespiratory Function TestsRisk FactorsUnited StatesasthmadietarylifestylemortalityNHANESOBS

Identifiers

PMID40946303
PMCPMC12434860

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.