Evidence map›Paper›PMID 40947591›Full record

ArticleGut and liver2026

A Nationwide Trend Analysis of

Seung In Seo, Su Youn Nam, Junwoo Jo, Chang Seok Bang, Moon Won Lee, Yoon Jin Choi, Woon Geon Shin

Abstract read
In one paragraph

Article in Gut and liver, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Treatment of Helicobacter pylori Infection in Korea: An Evidence-Based Analysis of the Upcoming 2025 Guideline.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Seung In SeoDepartment of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.ORCID 0000-0003-4417-0135
Su Youn NamDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID 0000-0002-5568-7714
Junwoo JoDepartment of Statistics, Kyungpook National University, Daegu, Korea.ORCID 0000-0002-5611-0714
Chang Seok BangInstitute for Liver and Digestive Diseases, Hallym University, Chuncheon, Korea.ORCID 0000-0003-4908-5431
Moon Won LeeDepartment of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.ORCID 0000-0002-8411-6398
Yoon Jin ChoiDepartment of Internal Medicine, Center for Gastric Cancer, National Cancer Center, Goyang, Korea.ORCID 0000-0002-1922-9388
Woon Geon ShinDepartment of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.ORCID 0000-0002-9851-5576

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aims: Despite numerous global changes in Methods: Using data from Korean Health Insurance Review and Assessment database spanning from January 2010 to December 2022, we extracted the performance code for Results: We analyzed the annual trends in standard triple therapy (STT; n=664,748), bismuth quadruple therapy (BQT; n=151,828), concomitant therapy (CT; n=3,034), sequential therapy (SEQ; n=1,612), and salvage treatment. Overall, STT use declined, with the use of 7-day STT decreasing but the use of 10- and 14-day STT increasing. The use of BQT as a first-line treatment consistently increased, and non-BQT (i.e., CT and SEQ) use also increased sharply since 2019. The tendency to adhere to the guideline changes was more pronounced in primary care clinics. Salvage treatment with BQT after STT failure exhibited a declining trend from 2010 to 2017, followed by an increase since 2018. Salvage treatment with levofloxacin triple therapy after BQT failure increased over time. Conclusions: This long-term nationwide trend analysis revealed that real-world prescriptions for

Indexed as

Anti-Bacterial AgentsGuideline AdherenceHelicobacter InfectionsHelicobacter pyloriPractice Patterns, Physicians'AdultAgedBismuthDrug Therapy, CombinationFemaleHumansMaleMiddle AgedPattern Analysis, MachinePractice Guidelines as TopicProton Pump InhibitorsAnti-Bacterial AgentsBismuthProton Pump InhibitorsDrug therapyGuidelineTrend

Identifiers

PMID40947591
PMCPMC12800674

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.