ArticleJournal of the American Chemical Society2025
An Alkyne-Directed Cleavage Approach for Activity-Based Cu(I) Sensing Reveals Manganese-Promoted Sensitization of Cuproptosis.
Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Manganese: biology, physiology and role in disease.Cell discovery · 2026Review
- Reduction in Hepatic Phosphatidylcholine Biosynthesis Promotes MASH Through Copper Deficiency.bioRxiv : the preprint server for biology · 2026Article
- Simultaneous Imaging of CuAngewandte Chemie (International ed. in English) · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Copper is an essential element for sustaining life. However, disruptions in copper homeostasis underpin disease, as illustrated by cuproptosis, an emerging form of cell death resulting from aberrant accumulation of copper pools in loosely bound, labile forms. Along these lines, activity-based sensing (ABS) offers a powerful strategy for tracking labile copper fluxes with metal and oxidation state selectivity by exploiting analyte reactivity for analyte detection. Traditional ABS probes for Cu(I), the major oxidation state of copper in cells, are selective but require O
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Registered trials
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