ReviewAngewandte Chemie (International ed. in English)2025
Biomedical Applications of Nanozymes: An Enzymology Perspective.
Review in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Nanozymes: bridging nanoscale characteristics and catalytic mechanisms for advanced biomedical applications.Journal of enzyme inhibition and medicinal chemistry · 2026Review
- Visual theranostic oral nanozymes for IBD from principles to preclinical design.Bioactive materials · 2026Review
- Catalytic lactate-regulatory nanosystems attenuate cellular senescence for atherosclerosis amelioration.Bioactive materials · 2026Article
- Sulfur-modified VRSC advances · 2026Article
- Engineering nanozymes for cancer theranostics: Chemical design, catalytic intelligence, and translational oncology frontiers.Translational oncology · 2026Review
- Metal-Organic Framework Multizyme Colloids with Joint Antioxidant and Protease Function.Langmuir : the ACS journal of surfaces and colloids · 2026Article
- Bionanotechnology at microplastic and nanoplastic interfaces: detection, adsorption and degradation.Nano convergence · 2026Review
- Hollow CuAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Immobilization of glucose oxidase and catalase on magnetite nanoparticles as functional catalyst supports.Journal of materials chemistry. C · 2026Article
- Resolving the issue of non-specific substrate oxidation in nanozyme-assisted colorimetric assays.Analytical and bioanalytical chemistry · 2026Article
- Moving Beyond Fenton-Based Peroxidase Nanozymes for Analytical Sensing: Perspectives on Nonradical Alternatives from Heterogeneous Catalysis.Analytical chemistry · 2026Review
- Nanozymes for Advanced Hemoglobin-Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- A Single Polyoxometalate Nanozyme for Cross-Reactive Thiol Array Sensing via pKa-Driven and Enrichment-Synergistic Strategy.Sensors (Basel, Switzerland) · 2026Article
- Atomically Precise Clusterzymes: A Programmable Optoelectronic Platform for Neuroscience.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Pseudo-two-dimensional multiphysics modeling of mass transport and pseudo-enzymatic kinetics in TiRSC advances · 2026Article
- Metal-Functionalized Nanozymes in Antibacterial Wound Management: Recent Advances and Future Perspectives.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Copper-based single-atom nanozymes: from fundamental insights to biomedical applications.Chemical science · 2026Review
- The Current Application Prospects of Nanomedicine in Renal Ischemia-Reperfusion Injury.International journal of nanomedicine · 2026Review
- Therapeutic Nanozymes in Rheumatoid Arthritis Treatment Through Disease Stage-Oriented Strategies.International journal of nanomedicine · 2026Review
- Tetrametallic Au@Ag-Pd-Pt Nanozyme with Surface-Exposed Active Sites for Enhanced Catalytic Activity.Nanomaterials (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Nanozymes are catalytic nanomaterials that transform enzyme substrates into their corresponding products, offering enhanced stability and a cost-effective alternative to traditional enzymes. As nanomaterials, they possess unique physicochemical properties and catalytic mechanisms distinct from those of enzymes. Such differences have profound, yet often neglected, implications in biomedical applications. In the context of enzymology, this review compares nanozymes and enzymes, with a focus on redox reactions. This review begins with the classification of nanozymes based on the types of reactions they catalyze, with the ability to exhibit multiple catalytic activities being a prevalent characteristic. The use of the Michaelis-Menten model for both enzymes and nanozymes is discussed in detail, and the Michaelis constant, maximum reaction rate, and turnover number values are compared. The performance of nanozymes in crowded environments and under extreme conditions is also compared to that of enzymes. We discuss the kinetic factors influencing nanozyme performance, the impact of active site shielding, and the activity under non-physiological conditions. We then compiled recent trends in the biomedical applications of nanozymes, focusing on both the production and scavenging of reactive oxygen species. This review links fundamental enzymology to nanozyme catalysis, providing a key reference for the rational use of nanozymes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.