Evidence map›Paper›PMID 40948521›Full record

ReviewAmerican journal of cancer research2025

Heterogeneity of monocytes in cancer.

Xinyue Zhang, Sitong Chen, Miao Shi, Jinjin Lou, Qichen Huang, Chunyan Li, Yanyan Huang, Liyun Xu

Abstract readReview
In one paragraph

Review in American journal of cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xinyue ZhangZhoushan Hospital, Postgraduate Training Base Alliance of Wenzhou Medical University Wenzhou, Zhejiang, China.
Sitong ChenCellular and Molecular Biology Laboratory, Zhoushan Hospital, Zhejiang University School of Medicine Zhoushan, Zhejiang, China.
Miao ShiCellular and Molecular Biology Laboratory, Zhoushan Hospital, Zhejiang University School of Medicine Zhoushan, Zhejiang, China.
Jinjin LouZhoushan Hospital, Postgraduate Training Base Alliance of Wenzhou Medical University Wenzhou, Zhejiang, China.
Qichen HuangZhoushan Hospital, Postgraduate Training Base Alliance of Wenzhou Medical University Wenzhou, Zhejiang, China.
Chunyan LiCellular and Molecular Biology Laboratory, Zhoushan Hospital, Wenzhou Medical University Zhoushan, Zhejiang, China.
Yanyan HuangCellular and Molecular Biology Laboratory, Zhoushan Hospital, Wenzhou Medical University Zhoushan, Zhejiang, China.
Liyun XuCellular and Molecular Biology Laboratory, Zhoushan Hospital, Wenzhou Medical University Zhoushan, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monocytes, a crucial element of the innate immune system, act as the primary cells in the body's immune response. Approved by the International Federation for Immunology in 2010, monocytes are categorized into three subsets based on the degree of cell surface molecule expression: classical monocytes, intermediate monocytes, and non-classical monocytes. Generally, different monocyte subsets have diverse responsibilities and can mutually transform to maintain the stability of the internal environment. Distinctions in functional characteristics and associations with diseases have been identified among the various monocyte subsets. This review aims to describe the expression and functions of monocytes in detail and discuss their roles in cancer immunity, which offers a novel approach for the diagnosis, treatment, and prognosis of tumors by exploring and summarizing the distribution of monocyte subsets in tumors. By delving into the distribution and functional characteristics of different monocyte subsets in tumors, it holds the promise of guiding individualized therapies and more precise tumor management.

Indexed as

cancersimmune responsesMonocytesprognosis

Identifiers

PMID40948521
PMCPMC12432559

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.