Evidence map›Paper›PMID 40948577›Full record

ArticlePulmonary circulation2025

Use of Dupilumab to Treat Cutaneous Complications of Continuous Prostacyclin Infusion in Pulmonary Hypertension: A Case Report and Review of Literature.

Nidhy P Varghese, Erin Ely, Rozmeen Fombin, Claire Champion, Elise Whalen

Abstract read
In one paragraph

Article in Pulmonary circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nidhy P VargheseDepartment of Pediatrics, Division of Pulmonology Baylor College of Medicine Houston Texas USA.ORCID https://orcid.org/0000-0003-4422-3065
Erin ElyTexas Children's Hospital Pulmonary Hypertension Center at the Texas Medical Center Houston Texas USA.
Rozmeen FombinTexas Children's Hospital Pulmonary Hypertension Center at the Texas Medical Center Houston Texas USA.
Claire ChampionDepartment of Pediatrics, Division of Pulmonology Baylor College of Medicine Houston Texas USA.
Elise WhalenDepartment of Pediatrics, Division of Pulmonology Baylor College of Medicine Houston Texas USA.ORCID https://orcid.org/0000-0002-6191-8881

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adhesive reactions are common complications of continuous treprostinil infusions, limiting their recommended use as a treatment for severe pulmonary hypertension. We present the case of a 10-year-old male with recurrent adhesive-related skin reactions, which compromised both subcutaneous and intravenous continuous treatment. Due to comorbid atopic dermatitis (AD), dupilumab was initiated to decrease skin reactions to adhesives. Within 48 h of initiation, skin reactions completely resolved. With sustained dupilumab treatment, he remains symptom-free and is successfully tolerating intravenous treprostinil infusion.

Indexed as

adhesivescellulitisdermatitiseczemapediatricsprostacyclinpulmonary hypertensionsubcutaneous infusiontreprostinil

Identifiers

PMID40948577
PMCPMC12426413

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.